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Biological Procedures Online, 2001 The study of parasitic protozoa plays a major role in cell biology, biochemistry and molecular biology. Numerous cytochemical techniques have been developed in order to unequivocally identify the nature of subcellular compartments.
Vannier-Santos Marcos, Lins Ulysses
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Iron sparing and recycling in a compartmentalized cell [PDF]
Current Opinion in Microbiology, 2013 This review focuses on economizing, prioritizing and recycling iron in Chlamydomonas, a reference organism for discovering mechanisms of acclimation to poor iron nutrition in the plant lineage. The metabolic flexibility of Chlamydomonas offers a unique opportunity to distinguish the impact of iron nutrition on photosynthetic versus respiratory ...
Blaby-Haas, Crysten E +1 more
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Microfluidic Compartmentalization Platforms for Single Cell Analysis [PDF]
Biosensors, 2022 Many cellular analytical technologies measure only the average response from a cell population with an assumption that a clonal population is homogenous. The ensemble measurement often masks the difference among individual cells that can lead to misinterpretation.
Xuhao Luo +3 more
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Imaging of PDE2- and PDE3-Mediated cGMP-to-cAMP Cross-Talk in Cardiomyocytes
Journal of Cardiovascular Development and Disease, 2018 Cyclic nucleotides 3′,5′-cyclic adenosine monophosphate (cAMP) and 3′,5′-cyclic guanosine monophosphate (cGMP) are important second messengers that regulate cardiovascular function and disease by acting in discrete subcellular microdomains.
Nikoleta Pavlaki, Viacheslav O. Nikolaev
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Studying GPCR/cAMP pharmacology from the perspective of cellular structure
Frontiers in Pharmacology, 2015 Signal transduction via G-protein coupled receptors (GPCRs) relies upon the production of cAMP and other signaling cascades. A given receptor and agonist pair, produce multiple effects upon cellular physiology which can be opposite in different cell ...
Peter T Wright +2 more
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Modulation in Wistar rats of blood corticosterone compartmentation by sex and a cafeteria diet. [PDF]
PLoS ONE, 2013 In the metabolic syndrome, glucocorticoid activity is increased, but circulating levels show little change. Most of blood glucocorticoids are bound to corticosteroid-binding globulin (CBG), which liver expression and circulating levels are higher in ...
María del Mar Romero +6 more
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Compartmentalized Production of Ceramide at the Cell Surface [PDF]
Journal of Biological Chemistry, 1995 Ceramide produced by the hydrolysis of sphingomyelin is an important cellular intermediate in hormone action. Here, we present evidence that interleukin 1 beta (IL-1 beta) binding to normal human fibroblasts initiates a lipid messenger cascade that takes place in a sphingomyelin-rich plasma membrane domain with the characteristics of caveolae.
P, Liu, R G, Anderson
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Abscisic acid dynamics in roots detected with genetically encoded FRET sensors
eLife, 2014 Cytosolic hormone levels must be tightly controlled at the level of influx, efflux, synthesis, degradation and compartmentation. To determine ABA dynamics at the single cell level, FRET sensors (ABACUS) covering a range ∼0.2–800 µM were engineered using ...
Alexander M Jones +5 more
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Horticulture Research, 2019 In developing apple fruit, metabolic compartmentation is poorly understood due to the lack of experimental data. Distinguishing subcellular compartments in fruit using non-aqueous fractionation has been technically difficult due to the excess amount of ...
Wasiye F. Beshir +6 more
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Journal of Cardiovascular Development and Disease, 2018 3′-5′-cyclic adenosine monophosphate (cAMP) is a signaling messenger produced in response to the stimulation of cellular receptors, and has a myriad of functional applications depending on the cell type.
Navneet K. Bhogal +2 more
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