Results 1 to 10 of about 17,196,917 (410)

Ultraviolet microscopy aids in cytological and biomedical research [PDF]

, 1967
Ultraviolet microscopy is used by cytologists and biochemists to study the morphological and physiological changes in the living cell under varied culture conditions.
Schlenk, F., Svihla, B.
core   +1 more source

Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]

, 2010
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel, Brimacombe, Claire L, Cao, Feng, Graf, Tyler N, Grove, Joe, Kane, Olivia J, Lohmann, Volker, Martinez, Laura E, McKeating, Jane A, Nahmias, Yaakov, Negash, Amina, Oberlies, Nicholas H, Owen, David M, Polyak, Stephen J, Pécheur, Eve-Isabelle, Tavis, John E, Wagoner, Jessica   +16 more
core   +1 more source

The contribution of age structure to cell population responses to targeted therapeutics [PDF]

, 2012
Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner.
Ackleh, Ackleh, Ainseba, Ainseba, Alarcón, Angulo, Angulo, Arino, Banks, Bekkal Brikci, Bekkal Brikci, Bernard, Calsina, Darren R. Tyson, Diekmann, Douglas, Doumic, Doumic, Dowling, Engel, Engl, Gabriel, Gabriel, Gerlee, Glenn F. Webb, Golubev, Gyllenberg, Gyllenberg, Gyllenberg, Hinow, Kostova, Lee, Liu, Mallet, Michel, Patel, Perthame, Perthame, Picart, Picart, Pierre Gabriel, Pilant, Pilant, Powathil, Quaranta, Quaranta, Ramis-Conde, Ribba, Rundell, Rundell, Shawn P. Garbett, Vito Quaranta, Webb   +52 more
core   +7 more sources

Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies

Computational and Structural Biotechnology Journal
The secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy, Giulia Lambiase, Sew Peak-Chew, Catarina Franco, Steven W. Wingett, Tim J. Stevens, Luigi Grassi, Noah Hitchcock, Cristina Sayago Ferreira, Diane Hatton, Elizabeth A. Miller, Rajesh K. Mistry   +13 more
doaj   +1 more source

Accurate RT-qPCR gene expression analysis on cell culture lysates [PDF]

, 2012
Gene expression quantification on cultured cells using the reverse transcription quantitative polymerase chain reaction (RT-qPCR) typically involves an RNA purification step that limits sample processing throughput and precludes parallel analysis of ...
Mestdagh, Pieter, Van Peer, Gert, Vandesompele, Jo   +2 more
core   +2 more sources

Saccharomyces cerevisiae morphological changes and cytokinesis arrest elicited by hypoxia during scale-up for production of therapeutic recombinant proteins

Microbial Cell Factories, 2018
Background Scaling up of bioprocesses represents a crucial step in the industrial production of biologicals. However, our knowledge about the impact of scale-up on the organism’s physiology and function is still incomplete.
Juan C. Aon, Ricardo C. Tecson, Vakhtang Loladze   +2 more
doaj   +1 more source

Low Cost, Adhesion Strength Based Cell Sorter [PDF]

, 2017
In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells.
Burtch, Emily, Kamga-Gninzeko, Franck, Mair, Devin, Saunders, Sarah   +3 more
core   +2 more sources

Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]

, 2008
DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core   +1 more source

Microvascular Endothelial Cell Culture.

Journal of Investigative Dermatology, 1989
Microvascular endothelial cells play a central role in inflammation, tumor metastasis, and wound healing. Methods to study these processes in vitro using cells isolated from adult skin, from the inner and the outer segments of the neontal foreskin, and from experimental animals are reviewed.
openaire   +2 more sources

Cell culture

, 2023
Published by MDPI ...
Weiskirchen, Sabine, Weiskirchen, Ralf, Schröder, Sarah K., Buhl, Eva Miriam   +3 more
openaire   +2 more sources