Results 111 to 120 of about 17,149,914 (409)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

PDMS-Based Microfluidic Devices for Cell Culture

Inventions, 2018
Microfluidic technology has affirmed itself as a powerful tool in medical and biological research by offering the possibility of managing biological samples in tiny channels and chambers.
S. Torino, B. Corrado, M. Iodice, G. Coppola   +3 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Low Cost, Adhesion Strength Based Cell Sorter [PDF]

, 2017
In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells.
Burtch, Emily, Kamga-Gninzeko, Franck, Mair, Devin, Saunders, Sarah   +3 more
core   +2 more sources

Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies

Computational and Structural Biotechnology Journal
The secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy, Giulia Lambiase, Sew Peak-Chew, Catarina Franco, Steven W. Wingett, Tim J. Stevens, Luigi Grassi, Noah Hitchcock, Cristina Sayago Ferreira, Diane Hatton, Elizabeth A. Miller, Rajesh K. Mistry   +13 more
doaj   +1 more source

Plant cell culture technology in the cosmetics and food industries: current state and future trends

Applied Microbiology and Biotechnology, 2018
The production of drugs, cosmetics, and food which are derived from plant cell and tissue cultures has a long tradition. The emerging trend of manufacturing cosmetics and food products in a natural and sustainable manner has brought a new wave in plant ...
R. Eibl, Philipp Meier, Irène Stutz, David Schildberger, T. Hühn, D. Eibl   +5 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Glial cell line-derived neurotrophic factor influences proliferation of osteoblastic cells [PDF]

, 2012
Little is known about the role of neurotrophic growth factors in bone metabolism. This study investigated the short-term effects of glial cell line-derived neurotrophic factor (GDNF) on calvarial-derived MC3T3-E1 osteoblasts.
Airaksinen, Baldassarre, Ben A. Scheven, Chen, Costantini, Cuccuru, De Ceuninck, Declercq, Edery, Figiel, Forander, Frost, Gale, Gao, Garcia, Gattei, Gattei, Glass, Gowen, Hashino, Hefferan, Hellmich, Janssens, Jiang, Kashani, Krieglstein, Kuno, Kurozumi, Lencel, Li, Luukko, Modrowski, Nakayama, Nanes, Nosrat, Nosrat, Paratcha, Paul R. Cooper, Peterziel, Rawlinson, Remy, Remy, Robinson, Saarma, Sariola, Scheven, Scheven, Shi, Subramaniam, van den Bos, Wang, Wang, Yajima, Yan, Yanaga, Zins, Zoe Gale   +56 more
core   +2 more sources

A Phytocomplex Obtained from Salvia officinalis by Cell Culture Technology Effectively Controls the Grapevine Downy Mildew Pathogen Plasmopara viticola [PDF]

, 2022
Isabella Busato, Oriana Bertaiola, Silvio Tundo, Chiara Guarnerio, Marco Lucchetta, Luca Sella, Giovanna Pressi, Francesco Favaron   +7 more
openalex   +1 more source

Microvascular Endothelial Cell Culture.

Journal of Investigative Dermatology, 1989
Microvascular endothelial cells play a central role in inflammation, tumor metastasis, and wound healing. Methods to study these processes in vitro using cells isolated from adult skin, from the inner and the outer segments of the neontal foreskin, and from experimental animals are reviewed.
openaire   +2 more sources