Results 131 to 140 of about 2,069,582 (340)

Comparing intra-uterine injection of mononuclear cells and platelet-rich plasma on the pregnancy rate of women with recurrent implantation failure: An RCT

International Journal of Reproductive BioMedicine
Background: Recurrent implantation failure (RIF) can be explained mainly by improper crosstalk between the embryo and endometrium. The T-helper1/T-helper2 profile balance influences effective embryo implantation.
Hoda Fazaeli, Azar Sheikholeslami, Zahra Ebrahimi, Naser Kalhor, Leila Naserpour   +4 more
doaj   +1 more source

Multi-Scale Kinetics Modeling for Cell Culture Process with Metabolic State Transition [PDF]

arXiv
To advance the understanding of cellular metabolisms and control batch-to-batch variations in cell culture processes, a multi-scale mechanistic model with a bottom-up and top-down structure was developed to simulate the dynamics of cell culture process undergoing metabolic state transitions. This model integrates interactions at the molecular, cellular,
arxiv  

THE EFFECT OF POLIOMYELITIS VIRUS ON HUMAN BRAIN CELLS IN TISSUE CULTURE [PDF]

, 1955
Mary Jane Hogue, Robert M. McAllister, A.E. Greene, L.L. Coriell   +3 more
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies

Computational and Structural Biotechnology Journal
The secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly ...
Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy, Giulia Lambiase, Sew Peak-Chew, Catarina Franco, Steven W. Wingett, Tim J. Stevens, Luigi Grassi, Noah Hitchcock, Cristina Sayago Ferreira, Diane Hatton, Elizabeth A. Miller, Rajesh K. Mistry   +13 more
doaj  

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

The Reversible and Irreversible Toxic Effects of Antihela Cell Rabbit Serum upon Human Cell Lines in Tissue Culture [PDF]

, 1958
Gérald Goldstein, Quentin N. Myrvik
openalex   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

AN INHIBITOR OF VIRAL ACTIVITY APPEARING IN INFECTED CELL CULTURES

, 1959
Monto Ho, John F. Enders
openalex   +1 more source

In Vitro and In Vivo Studies on a Tissue Culture Cell Line Derived from Normal Monkey Heart [PDF]

, 1958
L.L. Coriell, Robert M. McAllister, A. Greene, W. Flagg, Milton G. Tall, Bridget K. Wagner   +5 more
openalex   +1 more source