Results 11 to 20 of about 17,149,914 (409)
Complete Replication of Hepatitis C Virus in Cell Culture [PDF]
Science, 2005 Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell culture, which has slowed research progress on this important human pathogen.
B. Lindenbach +10 more
semanticscholar +2 more sources
Scientific Reports, 2020 One major challenge observed for the expression of therapeutic bispecific antibodies (BisAbs) is high product aggregates. Aggregates increase the risk of immune responses in patients and therefore must be removed at the expense of purification yields ...
Pritam Sinharoy +4 more
doaj +1 more source
A Novel 2.5D Culture Platform to Investigate the Role of Stiffness Gradients on Adhesion-Independent Cell Migration [PDF]
, 2014 Current studies investigating the role of biophysical cues on cell migration focus on the use of culture platforms with static material parameters. However, migrating cells in vivo often encounter spatial variations in extracellular matrix stiffness.
Asuri, Prashanth +2 more
core +7 more sources
Preservation media, durations and cell concentrations of short-term storage affect key features of human adipose-derived mesenchymal stem cells for therapeutic application [PDF]
PeerJ, 2017 Background Adipose-derived mesenchymal stem cells (ADSCs) have shown great potential in the treatment of various diseases. However, the optimum short-term storage condition of ADSCs in 2∼8 °C is rarely reported.
Fengli Zhang +5 more
doaj +2 more sources
European Journal of Clinical Microbiology and Infectious Diseases, 2020 In a preliminary clinical study, we observed that the combination of hydroxychloroquine and azithromycin was effective against SARS-CoV-2 by shortening the duration of viral load in Covid-19 patients.
B. La Scola +7 more
semanticscholar +1 more source
Cell & Bioscience, 2022 Extracellular vesicles (EVs) are cell-derived membrane structures exerting major effects in physiological as well as pathological processes by functioning as vehicles for the delivery of biomolecules to their target cells. An increasing number of effects
Ciarra Almeria +4 more
doaj +1 more source
Cell-Culture Measurements Using Voltage Oscillations [PDF]
, 2016 A comprehensive system for real-time monitoring of a set of cell-cultures using a Voltage Oscillation (VO) methodology is proposed. The main idea is to connect the bio-electrical elements (electrodes & cell-culture) in such a way that sequentially a ...
Huertas Sánchez, Gloria +5 more
core +1 more source
AMB Express, 2017 Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an
SooJin Han +5 more
doaj +1 more source
Molecular & Cellular Proteomics, 2002 Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and ...
Shao-En Ong +6 more
semanticscholar +1 more source
Expression of Tumor Assosiated and Epithelial-mesenchymal Transition Markers in 2d and 3d Cell Cultures of Mcf-7 [PDF]
, 2016 The target effects on the expression of epithelial-mesenchymal transition regulation molecules are promising for cancer therapy, including breast cancer.
Herheliuk, T. (Tetiana) +4 more
core +2 more sources