In vitro cytotoxic and genotoxic effects of donkey milk on lung cancer and normal cells lines
Czech Journal of Food Sciences, 2019 In vitro cytotoxic and genotoxic effects of donkey milk on cancer (A549) and normal (BEAS-2B) lung cell lines were investigated. The XTT and WST-1 tests as well as clonogenic assays were used to evaluate cytotoxicity.
Cetin Akca +5 more
doaj +1 more source
Development and cytotoxic response of two proliferative MDA- MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines [PDF]
, 2017 Triple-Negative Basal-Like tumors, representing 15 to 20% of breast cancers, are very aggressive and with poor prognosis. Targeted therapies have been developed extensively in preclinical and clinical studies to open the way for new treatment strategies.
arxiv +1 more source
Metabolic Regulatory Network Kinetic Modeling with Multiple Isotopic Tracers for iPSCs [PDF]
arXiv, 2023 The rapidly expanding market for regenerative medicines and cell therapies highlights the need to advance the understanding of cellular metabolisms and improve the prediction of cultivation production process for human induced pluripotent stem cells (iPSCs). In this paper, a metabolic kinetic model was developed to characterize underlying mechanisms of
arxiv
Fabrication, characterisation and performance of hydrophilic and super-hydrophilic silica as cell culture surfaces [PDF]
, 2012 We demonstrate a straightforward procedure for the controlled formation of silica films on tissue culture polystyrene (PS) surfaces. The films were formed by sequentially treating PS with polyaniline, glutaric dialdehyde and protein prior to silica ...
Boocock, DJ +4 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2020 The introduction of advanced therapy medicinal products (ATMPs) to the global pharma market has been revolutionizing the pharmaceutical industry and has opened new routes for treating various types of cancers and incurable diseases.
Roya Ramezankhani +21 more
doaj +1 more source
A low-cost, user-friendly rheo-optical compression assay to measure mechanical properties of cell spheroids in standard cell culture plates [PDF]
arXiv, 2023 The mechanical characterization of cell spheroids, one of the most widely used 3D biology models in vitro, is a hotspot of current research on the role played by the mechanical response of cells and tissues. The techniques proposed so far in the literature, while providing important scientific insights, require a specialized equipment and technical ...
arxiv
Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]
, 2017 Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C. +5 more
core +2 more sources
Systematic optimization of human pluripotent stem cells media using Design of Experiments. [PDF]
, 2015 Human pluripotent stem cells (hPSC) are used to study the early stages of human development in vitro and, increasingly due to somatic cell reprogramming, cellular and molecular mechanisms of disease.
Chailangkarn, Thanathom +2 more
core +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source