Results 41 to 50 of about 15,168,841 (359)
Frontiers in Molecular Biosciences, 2022 Type 2 diabetes mellitus (T2DM) is a growing global public health issue, and dipeptidyl peptidase-4 (DPP-4) is a potential therapeutic target in T2DM. Several synthetic anti-DPP-4 medications can be used to treat T2DM. However, because of adverse effects,
Sibhghatulla Shaikh +17 more
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Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
World Journal of Stem Cells, 2019 Three-dimensional (3D) culture systems are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than the monolayer cultures.
Nipha Chaicharoenaudomrung +2 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences, 2001 Genomics, proteomics, vaccinology, transgenics, stem cell—advances in all these areas critically stack on the shoulders of tissue culture, our ability to cultivate an organism's living cells in plastic dishes. Nutritional trial and error for decades of painstaking cell gardening laid the groundwork for the several thousand human primary cell explants ...
openaire +3 more sources
Assay and drug development technologies, 2014 Three-dimensional (3D) cell culture systems have gained increasing interest in drug discovery and tissue engineering due to their evident advantages in providing more physiologically relevant information and more predictive data for in vivo tests.
R. Edmondson +3 more
semanticscholar +1 more source
Intestinal Barrier, Claudins and Mycotoxins
Toxins, 2021 The intestinal barrier is the main barrier against all of the substances that enter the body. Proper functioning of this barrier guarantees maintained balance in the organism. Mycotoxins are toxic, secondary fungi metabolites, that have a negative impact
Marta Justyna Kozieł +2 more
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Improving the metabolic fidelity of cancer models with a physiological cell culture medium
Science Advances, 2019 Plasmax, a physiological cell culture medium, prevents metabolic artifacts imposed on cancer cells by commonly used media. Currently available cell culture media may not reproduce the in vivo metabolic environment of tumors.
J. Vande Voorde +9 more
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In vitro cytotoxic and genotoxic effects of donkey milk on lung cancer and normal cells lines
Czech Journal of Food Sciences, 2019 In vitro cytotoxic and genotoxic effects of donkey milk on cancer (A549) and normal (BEAS-2B) lung cell lines were investigated. The XTT and WST-1 tests as well as clonogenic assays were used to evaluate cytotoxicity.
Cetin Akca +5 more
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Towards Physiologic Culture Approaches to Improve Standard Cultivation of Mesenchymal Stem Cells
Cells, 2021 Mesenchymal stem cells (MSCs) are of great interest for their use in cell-based therapies due to their multipotent differentiation and immunomodulatory capacities.
Ilias Nikolits +4 more
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Evidence-based guidelines for controlling pH in mammalian live-cell culture systems
Communications Biology, 2019 A fundamental variable in culture medium is its pH, which must be controlled by an appropriately formulated buffering regime, since biological processes are exquisitely sensitive to acid–base chemistry.
J. Michl, K. Park, P. Swietach
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