Results 61 to 70 of about 17,196,917 (410)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

SARS-CoV-2-specific humoral and cellular immunity assessment in Peruvian vaccinated population: a cross-sectional study [PDF]

PeerJ
Background Evaluating both humoral and cellular immunity is essential for optimizing vaccination strategies and preventing post-pandemic SARS-CoV-2 outbreaks.
Marlon Yuri Garcia-Paitan, Salyoc Tapia-Rojas, Hector Santiago Alvarez Vega, Javier Enciso-Benavides, Maria J. Pons, Ana Mayanga-Herrera   +5 more
doaj   +2 more sources

Two Decades of Global Progress in Authorized Advanced Therapy Medicinal Products: An Emerging Revolution in Therapeutic Strategies

Frontiers in Cell and Developmental Biology, 2020
The introduction of advanced therapy medicinal products (ATMPs) to the global pharma market has been revolutionizing the pharmaceutical industry and has opened new routes for treating various types of cancers and incurable diseases.
Roya Ramezankhani, Roya Ramezankhani, Shukoofeh Torabi, Shukoofeh Torabi, Neda Minaei, Neda Minaei, Hoda Madani, Hoda Madani, Siamak Rezaeiani, Siamak Rezaeiani, Seyedeh Nafiseh Hassani, Seyedeh Nafiseh Hassani, Adrian P. Gee, Massimo Dominici, Daniela Nascimento Silva, Daniela Nascimento Silva, Hossein Baharvand, Hossein Baharvand, Hossein Baharvand, Ensiyeh Hajizadeh-Saffar, Ensiyeh Hajizadeh-Saffar, Ensiyeh Hajizadeh-Saffar   +21 more
doaj   +1 more source

Intestinal Barrier, Claudins and Mycotoxins

Toxins, 2021
The intestinal barrier is the main barrier against all of the substances that enter the body. Proper functioning of this barrier guarantees maintained balance in the organism. Mycotoxins are toxic, secondary fungi metabolites, that have a negative impact
Marta Justyna Kozieł, Maksymilian Ziaja, Agnieszka Wanda Piastowska-Ciesielska   +2 more
doaj   +1 more source

Optimized exosome isolation protocol for cell culture supernatant and human plasma

Journal of Extracellular Vesicles, 2015
Extracellular vesicles represent a rich source of novel biomarkers in the diagnosis and prognosis of disease. However, there is currently limited information elucidating the most efficient methods for obtaining high yields of pure exosomes, a subset of ...
R. Lobb, Melanie Becker, Shu Wen Wen, Christina S. F. Wong, A. Wiegmans, Antoine Leimgruber, A. Möller   +6 more
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

FOXO3a/PI3K/Akt pathway participates in the ROS- induced apoptosis triggered by α-ZEL and β-ZEL

Scientific Reports
Zearalenone (ZEN), an estrogenic mycotoxin, is one of the most common food and feed contaminants. Also, its metabolites α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL) are considered to induce oxidative stress, however its effect in prostate cells is not ...
Dominika Ewa Habrowska-Górczyńska, Marta Justyna Kozieł, Kinga Anna Urbanek, Karolina Kowalska, Agnieszka Wanda Piastowska-Ciesielska   +4 more
doaj   +1 more source

Extracellular matrix of lung scaffolds submitted to different means of sterilization: a systematic review [version 1; peer review: 1 approved, 2 approved with reservations]

F1000Research
Chronic respiratory diseases often necessitate lung transplantation due to irreversible damage. Organ engineering offers hope through stem cell-based organ generation. However, the crucial sterilization step in scaffold preparation poses challenges. This
Luis Vicente Franco Oliveira, Giuseppe Insalaco, Renata K. Palma, Rodolfo P. Vieira, Deise A. A. P. Oliveira, Rodrigo F. Oliveira, Iransé Oliveira-Silva, Miria C. Oliveira, Diego A. C. P. G. Mello, Andressa D. Cereta, Adriano L. Fonseca, Joao Pedro R. Afonso, Ricardo S. Moura   +12 more
doaj   +1 more source

Towards Physiologic Culture Approaches to Improve Standard Cultivation of Mesenchymal Stem Cells

Cells, 2021
Mesenchymal stem cells (MSCs) are of great interest for their use in cell-based therapies due to their multipotent differentiation and immunomodulatory capacities.
Ilias Nikolits, Sabrina Nebel, Dominik Egger, Sebastian Kreß, Cornelia Kasper   +4 more
doaj   +1 more source

Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. [PDF]

, 2017
The culture of human limbal epithelial stem/progenitor cells (LSCs) in the presence of animal components poses the risk of cross-species contamination in clinical applications.
Chen, Luxia, Deng, Sophie X, González, Sheyla   +2 more
core   +1 more source