Results 81 to 90 of about 17,196,917 (410)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Tracing blastomere fate choices of early embryos in single cell culture [PDF]

open access: yes, 2010
Blastomeres of early vertebrate embryos undergo numerous fate choices for division, motility, pluripotency maintenance and restriction culminating in various cell lineages.
Chang Ming Li   +11 more
core   +1 more source

Meeting report: a hard look at the state of enamel research. [PDF]

open access: yes, 2017
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D   +13 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Gel-Based Approaches to Vegan Leather: Opportunities and Challenges in Mimicking Leather Properties

open access: yesGels
Recently, increased global awareness of environmental sustainability and ethical consumerism has amplified the demand for sustainable alternatives to animal-derived leather.
Soon Mo Choi   +4 more
doaj   +1 more source

Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability

open access: yesmAbs, 2022
With the aim of increasing protein productivity of Chinese hamster ovary (CHO) cells, we sought to generate new CHO hosts with favorable biomanufacturing phenotypes and improved functionality.
Lina Chakrabarti   +10 more
doaj   +1 more source

Single-Cell Analysis of CHO Cells Reveals Clonal Heterogeneity in Hyperosmolality-Induced Stress Response

open access: yesCells, 2022
Hyperosmolality can occur during industrial fed-batch cultivation processes of Chinese hamster ovary (CHO) cells as highly concentrated feed and base solutions are added to replenish nutrients and regulate pH values. Some effects of hyperosmolality, such
Nadiya Romanova   +5 more
doaj   +1 more source

Brilacidin Demonstrates Inhibition of SARS-CoV-2 in Cell Culture [PDF]

open access: gold, 2021
Allison Bakovic   +7 more
openalex   +1 more source

An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure. [PDF]

open access: yes, 2020
The development of an in vitro system in which human primordial germ cell-like cells (hPGCLCs) are generated from human pluripotent stem cells (hPSCs) has been invaluable to further our understanding of human primordial germ cell (hPGC) specification ...
Bower, Grace   +9 more
core  

Proliferation versus Differentiation: Redefining Retinoic Acids Role. [PDF]

open access: yes, 2018
Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al.
Mosher, Kira, SCHAFFER, David
core   +1 more source

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