Results 31 to 40 of about 2,848,210 (396)
Dental Research Journal, 2021 Background: Squamous cell carcinoma (SCC) is the most common oral malignancy with high rate of mortality. Cisplatin, as the most effective chemotherapy drug, has side effects.
Fatima Bijani +5 more
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Frontiers in Molecular Biosciences, 2021 Skeletal reconstruction is necessary in cases of bone defects created by tumors, trauma, and abnormalities. Regeneration of bone defects remains a critical problem, and current approaches are based on biocompatible scaffolds. Spheroids represent a simple
Iñigo Gaitán-Salvatella +4 more
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Osteostatin potentiates the bioactivity of mesoporous glass scaffolds containing Zn2+ ions in human mesenchymal stem cell cultures [PDF]
Acta Biomaterialia. 89 (2019) 359-371, 2021 There is an urgent need of biosynthetic bone grafts with enhanced osteogenic capacity. In this study, we describe the design of hierarchical meso-macroporous 3D-scaffolds based on mesoporous bioactive glasses (MBGs), enriched with the peptide osteostatin and Zn2+ ions, and their osteogenic effect on human mesenchymal stem cells (hMSCs) as a preclinical
arxiv +1 more source
Van Tıp Dergisi, 2022 INTRODUCTION: Glioblastoma multiforme (GBM) is one of the most common and deadliest primary brain tumors. Despite standard treatments such as surgical resection, radiation, and high-dose chemotherapy, the average survival time of patients after diagnosis
Mehmet Eşref Alkış
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Cells, 2022 Inadequacy of most animal models for drug efficacy assessments has led to the development of improved in vitro models capable of mimicking in vivo exposure scenarios.
Hadi Hashemzadeh +5 more
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Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation [PDF]
, 2023 Ascertaining the collective viability of cells in different cell culture conditions has typically relied on averaging colorimetric indicators and is often reported out in simple binary readouts. Recent research has combined viability assessment techniques with image-based deep-learning models to automate the characterization of cellular properties ...
arxiv +1 more source
Nuclear DNA and protein content evaluation in Taxus plant cell cultures using multiparameter flow cytometry [PDF]
, 2009 Plant cell cultures of Taxus provide the most reliable production methods for the anti-cancer drug paclitaxel. In order to comprehend the inherent culture heterogeneity and production variability in cell cultures, it is essential that the cellular ...
Amit Shavit +2 more
core +2 more sources
Environmental monitoring of Mycobacterium bovis in badger feces and badger sett soil by real-time PCR, as confirmed by immunofluorescence, immunocapture, and cultivation [PDF]
, 1999 Real-time PCR was used to detect and quantify Mycobacterium bovis cells in naturally infected soil and badger faeces. Immunomagnetic capture, immunofluorescence and selective culture confirmed species identification and cell viability.
Sweeney, F. P. +6 more
core +4 more sources
Cell culture techniques in gastrointestinal research: Methods, possibilities and challenges
Indian Journal of Pathology and Microbiology, 2021 Cell culture is one of the most valuable tools which is being applied in both fundamental and applied gastrointestinal research. The cells are isolated from their natural location (in vivo) and further propagated in vitro or artificial environment and ...
Gaur Preksha +2 more
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Regulating MDA-MB-231 breast cancer cell adhesion on laser-patterned surfaces with micro- and nanotopography [PDF]
Biointerphases 17, 021002 (2022), 2022 Breast cancer is the most common type of cancer observed in women. Communication with the tumor microenvironment allows invading breast cancer cells, such as triple negative breast cancer cells, to adapt to specific substrates. The substrate topography modulates the cellular behavior, among other factors.
arxiv +1 more source