Results 31 to 40 of about 2,740,660 (385)

Evaluation of apoptotic effect of crocin, cisplatin, and their combination in human oral squamous cell carcinoma cell line HN5

open access: yesDental Research Journal, 2021
Background: Squamous cell carcinoma (SCC) is the most common oral malignancy with high rate of mortality. Cisplatin, as the most effective chemotherapy drug, has side effects.
Fatima Bijani   +5 more
doaj   +1 more source

Investigation of Treatment Potential of O-Vanillin Containing Schiff Base Ligand and Pd(II) Complex in Glioblastoma Multiforme Cells and Efficiency of Electroporation

open access: yesVan Tıp Dergisi, 2022
INTRODUCTION: Glioblastoma multiforme (GBM) is one of the most common and deadliest primary brain tumors. Despite standard treatments such as surgical resection, radiation, and high-dose chemotherapy, the average survival time of patients after diagnosis
Mehmet Eşref Alkış
doaj   +1 more source

The changing role of cell culture in the generation of transgenic livestock [PDF]

open access: yes, 1999
Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Farini, E, Webster, J, Whitelaw, C B
core   +1 more source

Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss [PDF]

open access: yes, 2005
This review on the role of neurofilaments as surrogate markers for axonal degeneration in neurological diseases provides a brief background to protein synthesis, assembly, function and degeneration.
Petzold, A
core   +1 more source

Optimized Primary Culture and Subculture of Granulosa Cells

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Primordial follicle includes an oocyte surrounded by a layer of somatic cells called Granulosa Cells (GCs). GCs, also known as nurse cells, are an important protective element for the growth and survival of oocytes.
Nadia Fallah   +4 more
doaj  

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

open access: yes, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching   +17 more
core   +1 more source

An Modified Primary Culture Method of Breast Cancer-associated Fibroblasts

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To establish a rapid and high efficient method of primary culture of BCAFs by improving primary culture methods of common breast cancer-associated fibroblasts (BCAFs).
LI Zhiyong, BAI Xue, CAI Huiyun
doaj   +1 more source

Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates

open access: yesBioengineering, 2020
Human embryonic stem cell-derived mesenchymal progenitor (hES-MP) cells are mesenchymal-like cells, derived from human embryonic stem cells without the aid of feeder cells. They have been suggested as a potential alternative to mesenchymal stromal cells (
Sandra M. Jonsdottir-Buch   +2 more
doaj   +1 more source

Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42

open access: yesFrontiers in Neuroscience, 2023
Alzheimer’s disease (AD) is a devastating neurodegenerative condition with no effective treatments. Recent research highlights the role of NMDA receptors in AD development, as excessive activation of these receptors triggers excitotoxicity. Memantine, an
Nataliia M. Rozumna   +2 more
doaj   +1 more source

Evaluation of a composite skin substitute to treat venous stasis ulcers: a pilot study

open access: yesBrazilian Journal of Transplantation, 2006
Introduction: Venous leg ulcers represent a therapeutic challenge, and they are associated to significant morbidity and cost. Many advances have been made to develop and apply biological skin substitutes, showing they can be beneficial for patients with
Paula Dadalti-Granja   +7 more
doaj   +1 more source

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