Results 71 to 80 of about 1,114,098 (265)

The Alliance for Cellular Signaling Plasmid Collection: A Flexible Resource for Protein Localization Studies and Signaling Pathway Analysis [PDF]

, 2007
Cellular responses to inputs that vary both temporally and spatially are determined by complex relationships between the components of cell signaling networks.
Bryan, Heather, Chandy, Grischa, Chang, Mi Sook, Coutre, Sam, Dhandapani, Kavitha, Driver, Adrienne, Fraser, Iain D. C., Fung, Eileen, Gehrig, Elizabeth, Kivork, Christine, Lee, Genie, Liu, Jamie, Lyon, Stephen, Maer, Andreia, Meyer, Tobias, Mi, Qingli, Ning, Yuhong, O'Rourke, Nancy, Park, Wei Sun, Randhawa, Baljinder, Santat, Leah, Saunders, Brian, Simon, Melvin I., Subramaniam, Shankar, Verghese, Mary, Wall, Estelle, Whalen, James, Zavzavadjian, Joelle R., Zhu, Xiaocui   +28 more
core   +1 more source

A thin layer angiogenesis assay: a modified basement matrix assay for assessment of endothelial cell differentiation [PDF]

, 2014
BACKGROUND: Basement matrices such as Matrigel™ and Geltrex™ are used in a variety of cell culture assays of anchorage-dependent differentiation including endothelial cell tube formation assays.
A Li, AD Pierce, Andrew Hibbert, Ashton Faulkner, CA Staton, CA Staton, CA Staton, Caroline Wheeler-Jones, CE Clarkin, David Bishop-Bailey, E Garonna, F Vegran, G Wu, JJ Logie, L Piqueras, LS Cooley, M Ma, M Michaelis, M Schleicher, ME Capozzi, O Coutelle, RM Arantes, Robert Purcell, S Muses, Sally Latham, Scott Thomson, W Pendergrass, Wendy L Hall, X Zhao   +28 more
core   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Microengineered synthetic cellular microenvironment for stem cells [PDF]

, 2012
Stem cells possess the ability of self‐renewal and differentiation into specific cell types. Therefore, stem cells have great potentials in fundamental biology studies and clinical applications.
Fu, Jianping, Sun, Yubing, Weng, Shinuo
core   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold

, 2018
A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells.
Beliaev, Dmitry, Krause, Andrew L., Van Gorder, Robert A., Waters, Sarah L.   +3 more
core  

A two-fluid model for tissue growth within\ud a dynamic flow environment [PDF]

, 2008
We study the growth of a tissue construct in a perfusion bioreactor, focussing on its response to the mechanical environment. The bioreactor system is modelled as a two-dimensional channel containing a tissue construct through which a flow of culture ...
Byrne, H. M., O'Dea, R. D., Waters, S. L.   +2 more
core  

Microheated substrates for patterning cells and controlling development

, 2005
Here, we seek to control cellular development by devising a means through which cells can be subjected to a microheated environment in standard culture conditions.
Everett, W.N., Liu, M.H.H., Ma, Y.X., Moran, P.M., Shu, W.M., Spearing, S.M., Sue, H.J., Trigg, A., Wang, S., Zhang, Q.X.   +9 more
core   +1 more source

Tissue Culture Techniques in the Study of Cell Photobiology and Phototoxicity

Journal of Investigative Dermatology, 1970
Tissue culture monolayers exposed to 13 photosensitizing compounds demonstrated a phototoxic effect resulting in death of the cells when exposed to either broad spectrum or monochromatic ultraviolet or visible light of appropriate wavelength. Drug alone, light alone, and 2 non-photosensitizing chemicals with the light induced no such effect.
Robert G. Freeman, Wendy Murtishaw, John M. Knox   +2 more
openaire   +3 more sources

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source