Results 91 to 100 of about 583,264 (306)

Development of a sensitive cell culture system to assess prion infectivity and the efficacy of prion decontamination technologies [PDF]

, 2012
Creutzfeldt-Jakob disease (CJD) can be iatrogenically transmitted during transplants, grafts and transfusions from CJD infected donors and also contaminated surgical instruments.
Secker, Thomas
core  

A Brief History of Cell Culture: From Harrison to Organs-on-a-Chip [PDF]

This comprehensive overview of the historical milestones in cell culture underscores key breakthroughs that have shaped the field over time. It begins with Wilhelm Roux’s seminal experiments in the 1880s, followed by the pioneering efforts of Ross ...
Ribeiro-Paes, João Tadeu [UNESP], Dias, Marlon Lemos, João Tadeu Ribeiro-Paes, Lívero, Francislaine Aparecida dos Reis, Julia Amanda Rodrigues Fracasso, Francislaine Aparecida dos Reis Lívero, Marco Aurélio Lucio, Marlon Lemos Dias, Azevedo, Maurício Fogaça, Castro, Mateus Vidigal de, Lucas Pires Guarnier, Mateus Vidigal de Castro, Lincoln Gozzi Moro, Fracasso, Julia Amanda Rodrigues [UNESP], Lucio, Marco Aurélio, Maurício Fogaça Azevedo, Moro, Lincoln Gozzi, Guarnier, Lucas Pires   +17 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

In vitro modulation of proinflammatory and proteolytic activities of Porphyromonas gingivalis by selected lactobacilli

Journal of Oral Microbiology
Objective The aim of the present study was to characterize the antimicrobial and anti-inflammatory activities of postbiotics from lactic acid bacteria against Porphyromonas gingivalis.Material and methods The anti-P.
Johana R. Naja, Leyla Desparois, Elvira M. Hebert, Maria Elena Fátima Nader, Lucila Saavedra, Carlos J. Minahk, Vanessa P. Houde   +6 more
doaj   +1 more source

An Extensive Method for Maintenance of Sterility in Mammalian Cell Culture Laboratory Routine

Challenges, 2017
Cell culture laboratories are designed to secure sterile environments for biological studies, and its susceptibility to biological contaminants is a major problem for researchers.
Selcen Çelik-Uzuner, Uğur Uzuner
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Galactosylation of rat natural scaffold for MSC differentiation into hepatocyte-like cells: A comparative analysis of 2D vs. 3D cell culture techniques. [PDF]

Biochem Biophys Rep, 2023
Vazirzadeh M, Azarpira N, Vosough M, Ghaedi K.   +3 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts. [PDF]

Front Cell Dev Biol, 2021
Smith LA, Hidalgo Aguilar A, Owens DDG, Quelch RH, Knight E, Przyborski SA.   +5 more
europepmc   +1 more source

History of Cell Culture Techniques

The American Biology Teacher, 2010
Culturing Life: How Cells Became Technologies. By Hannah Landecker . 2007. Harvard University Press (ISBN 9780674034761). 276 pages. Paperback. $$18.95. Cell culture techniques have shaped the scope of biology since the start of the 20th century and are responsible for major advances in biomedicine.
openaire   +1 more source