Results 111 to 120 of about 8,365,967 (315)

Cell cycle regulated expression of the WHI7 Start repressor gene [PDF]

Periodic transcriptional waves along the cell cycle ensure the accurate progression of the different cell cycle phases through the timely regulated expression of cell cycle proteins.
Ros Carrero, Cristina, Gomar Alba, Mercè, Igual García, Juan Carlos   +2 more
core   +1 more source

A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes [PDF]

, 2012
The respiratory metabolic cycle in budding yeast (Saccharomyces cerevisiae) consists of two phases most simply defined phenomenologically: low oxygen consumption (LOC) and high oxygen consumption (HOC).
Airoldi, Edoardo|, Airoldi, E.M., Airoldi, EM, Airoldi, Edoardo M, Botstein, D., van Oudenaarden, Alexander, Airoldi, Edoardo, Van Oudenaarden, A, Botstein, David, Slavov, Nikolai G, Botstein, D, Slavov, N., Airoldi, Edoardo M., Slavov, N, van Oudenaarden, A., Slavov, Nikolai   +15 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair [PDF]

, 2008
Background: The H69CIS200 and H69OX400 cell lines are novel models of low-level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather the resistant cell lines have a cell
Davey, Ross, Stordal, Britta, Stordal, B., Davey, R.   +3 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The terminal basal mitosis of chicken retinal Lim1 horizontal cells is not sensitive to cisplatin-induced cell cycle arrest

, 2014
For proper development, cells need to coordinate proliferation and cell cycle-exit. This is mediated by a cascade of proteins making sure that each phase of the cell cycle is controlled before the initiation of the next.
Thyselius, Malin, Hallböök, Finn, Shirazi Fard, Shahrzad,, Hallböök, Finn,, Shirazi Fard, Shahrzad, All-Ericsson, Charlotta, Thyselius, Malin,   +6 more
core   +1 more source

Phosphatase POPX2 interferes with cell cycle by interacting with Chk1

, 2020
Protein-protein interaction network analysis plays critical roles in predicting the functions of target proteins. In this study, we used a combination of SILAC-MS proteomics and bioinformatic approaches to identify Checkpoint Kinase 1 (Chk1) as a ...
Kim, Pu Rum, Lee, Raphael Tze Chuen, Koon, Yen Ling, Koh, Dylan Hong Zheng, Chiam, Keng-Hwee, Koh, Cheng-Gee, Azizan, Farouq   +6 more
core   +1 more source

Nuclear reprogramming: kinetics of cell cycle and metabolic progression as determinants of success [PDF]

, 2012
Establishment of totipotency after somatic cell nuclear transfer (NT) requires not only reprogramming of gene expression, but also conversion of the cell cycle from quiescence to the precisely timed sequence of embryonic cleavage.
Franchesca Dawn Houghton (171722), Tsurumi Chizuko, Martin Johannes Pfeiffer (171732), Kanzler, Benoit, Fuellen, Georg, Pfeiffer, M., Tsurumi, Chizuko, Siatkowski Marcin, Benoit Kanzler (171742), Boiani, Michele, Esteves, T., Fuellen, G., Michele Boiani, Houghton, F., Georg Fuellen, Esteves Telma Cristina, Pfeiffer, Martin Johannes, Fuellen Georg, Balbach, S., Kanzler, B., Esteves, Telma Cristina, Benoit Kanzler, Kanzler Benoit, Boiani Michele, Telma Cristina Esteves, Michele Boiani (171751), Siatkowski, Marcin, Houghton Franchesca Dawn, Marcin Siatkowski, Balbach, Sebastian Thomas, Boiani, M., Georg Fuellen (16022), Telma Cristina Esteves (171719), Marcin Siatkowski (171726), Franchesca Dawn Houghton, Sebastian Thomas Balbach (171715), Chizuko Tsurumi (171736), Pfeiffer Martin Johannes, Siatkowski, M., Houghton, Franchesca Dawn, Martin Johannes Pfeiffer, Chizuko Tsurumi, Balbach Sebastian Thomas, Tsurumi, C., Sebastian Thomas Balbach   +44 more
core   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Dissection of a Redox Relay: H2O2-Dependent Activation of the Transcription Factor Pap1 through the Peroxidatic Tpx1-Thioredoxin Cycle

Cell Reports, 2013
In fission yeast, the transcription factor Pap1 undergoes H2O2-dependent oxidation that promotes its nuclear accumulation and the activation of an antioxidant gene program.
Isabel A. Calvo, Susanna Boronat, Alba Domènech, Sarela García-Santamarina, José Ayté, Elena Hidalgo   +5 more
doaj   +1 more source