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The Plant Cell Cycle

Annual Review of Plant Biology, 2003
Cell division in plants is controlled by the activity of cyclin-dependent kinase (CDK) complexes. Although this basic mechanism is conserved with all other eukaryotes, plants show novel features of cell-cycle control in the molecules involved and their regulation, including novel CDKs showing strong transcriptional regulation in mitosis.
Walter, Dewitte, James A H, Murray
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Finishing the Cell Cycle

Journal of Theoretical Biology, 1999
The eukaryotic cell division cycle consists of two characteristic states: G1, when replication origins of chromosomes are in a pre-replicative state, and S/G2/M, when they are in a post-replicative state (Nasmyth, 1995). Using straightforward biochemical kinetics, we show that these two states can be created by antagonistic interactions between cyclin ...
B, Novák   +5 more
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Evolution of the cell cycle

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995
Abstract Cell proliferation involves duplication of all cell constituents and their more-or-less equal segregation to daughter cells. It seems probable that the performance of primitive cell-like structures would have been dogged by poor duplication and segregation fidelity, and by parasitism. This favoured evolution of the genome and
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The cell cycle of archaea

Nature Reviews Microbiology, 2013
Growth and proliferation of all cell types require intricate regulation and coordination of chromosome replication, genome segregation, cell division and the systems that determine cell shape. Recent findings have provided insight into the cell cycle of archaea, including the multiple-origin mode of DNA replication, the initial characterization of a ...
Ann-Christin, Lindås, Rolf, Bernander
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Retinoblastoma cell cycling

Cytometry, 1991
AbstractTechniques for the measurement of bromodeoxyuridine (BrdUrd) positive cells generally include either microscopic evaluation of paraffin embedded sections or measurements on cell suspensions using a fluorescent activated cell sorter. The accuracy of these measurements and their correlations can be affected by a number of technical and intrinsic ...
S, Kaleta-Michaels   +3 more
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Cancer Cell Cycles

Science, 1996
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
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Dormancy and the Cell Cycle

2006
The localization of the Kip-related proteins to meristematic regions suggests that these proteins might be associated with dormancy regulation. Additionally, the localization of chromatin remodeling to specific genes and loci may reveal the important regulation mechanisms for the dormant state.
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Checking on the cell cycle

Journal of Cellular Biochemistry, 1998
Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor ...
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Cell cycle control in cancer

Nature Reviews Molecular Cell Biology, 2021
Helen K Matthews   +2 more
exaly  

Cell Cycle Control

2002
The cell cycle is the sequence of events through which a cell duplicates its genome, grows, and divides. Major cell cycle transitions are driven by cyclin-dependent kinases and other kinases. Ubiquitin-mediated protein degradation is also a major driving force for cell cycle transitions.
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