Results 251 to 260 of about 8,365,967 (315)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Exercise training promotes neurogenesis in the adult hippocampus with a particular focus on cell cycle regulation. [PDF]

Front Sports Act Living
Wang XT, Wang J, Zhao XJ.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

CDCA7 Promotes Neuroblastoma Proliferation via Regulating the Cell Cycle. [PDF]

Iran J Biotechnol
Yuan W, Huang X, Luo R, Yu D, Pan Y, Du H, Ma X, Xiang Y.   +7 more
europepmc   +1 more source

Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

Molecular Cancer
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker, Gen Sheng Wu, Wafik S El-Deiry   +6 more
doaj   +1 more source

Probabilistic modeling of cell cycle dynamics in response to cell cycle targeting chemotherapy drugs to guide treatment strategies. [PDF]

PLoS Comput Biol
Ma C, Gurkan-Cavusoglu E.
europepmc   +1 more source

The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle. [PDF]

Elife
Hammond T, Choi JB, Membreño MW, Demeter J, Ng R, Bhattacharya D, Nguyen TN, Hartmann GG, Colon CI, Bossard C, Skotheim JM, Jackson PK, Pasca AM, Rubin SM, Sage J.   +14 more
europepmc   +1 more source

ZFHX4 is necessary for dopaminergic neuron differentiation and controls cell cycle by regulating LIN28A. [PDF]

Stem Cell Reports
Valceschini E, Gomez Ramos B, Ohnmacht J, Ginolhac A, Catillon M, Gerard D, Gaigneaux A, Kyriakis D, Grzyb K, Glaab E, Grünewald A, Skupin A, Sauter T, Krüger R, Sinkkonen L.   +14 more
europepmc   +1 more source

Hsp70 is phosphorylated in a conserved response to DNA damage and contributes to cell cycle control. [PDF]

Elife
Moss T, Wooldredge A, Bhakta K, Cronin M, Gestwicki JE, Mukherjee S.   +5 more
europepmc   +1 more source