Results 251 to 260 of about 1,815,617 (316)

Mechanistic Insights into Threonine Tyrosine Kinase Mediated Cell Cycle Regulation in Triple-negative Breast Cancer. [PDF]

Cancer Genomics Proteomics
Tang S, Zheng J, Zhang Y, Zeng LI, Wang J, Zhang S, Chen Y, Yin Q, Zheng X.   +8 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Mechanistic origins of temperature scaling in the early embryonic cell cycle. [PDF]

Nat Commun
Rombouts J, Tavella F, Vandervelde A, Phong C, Ferrell JE, Yang Q, Gelens L.   +6 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Control of CDK activity and the cell cycle by CKS proteins

Curran JF, Basu S, Auchynnikava T, Nurse P.   +3 more
europepmc   +1 more source

Crotonoside exerts anti-colorectal cancer effects by suppressing KIF20A to regulate the cell cycle. [PDF]

Sci Rep
Zhang Y, Sun J, Chen Z.
europepmc   +1 more source

Phosphoproteomic identification of Mos-MAPK targets in meiotic cell cycle and asymmetric oocyte divisions. [PDF]

J Cell Biol
Avilov I, Horokhovskyi Y, Mehta P, Welp L, Jakobi J, Cai M, Orzechowski A, Urlaub H, Liepe J, Lenart P.   +9 more
europepmc   +1 more source

Spatial Chromatin Organization Across the Cell Cycle: Insights from Auxin-Inducible Protein Depletion. [PDF]

Cells
Nurislamov A, Yunusova A.
europepmc   +1 more source

CENcyclopedia: dynamic landscape of kinetochore architecture throughout the cell cycle. [PDF]

Nat Commun
Chen YC, Kilic E, Wang E, Rossman W, Suzuki A.   +4 more
europepmc   +1 more source

Editor's Note on 'Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins'. [PDF]

Nucleic Acids Res
europepmc   +1 more source