Mad2, Bub3, and Mps1 regulate chromosome segregation and mitotic synchrony in Giardia intestinalis, a binucleate protist lacking an anaphase-promoting complex. [PDF]
, 2014 The binucleate pathogen Giardia intestinalis is a highly divergent eukaryote with a semiopen mitosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint complex (MCC) proteins.
Cande, W Zacheus, Vicente, Juan-Jesus
core +2 more sources
A Method for Analyzing the Ubiquitination and Degradation of Aurora-A
Biological Procedures Online, 2002 The cell cycle machinery consists of regulatory proteins that control the progression through the cell cycle ensuring that DNA replication alternates with DNA segregation in mitosis to maintain cell integrity.
Klotzbucher Andrea +3 more
doaj +1 more source
Hi-throughput gene expression analysis at the level of single proteins using a microfluidic turbidostat and automated cell tracking [PDF]
arXiv, 2012 We have developed a method combining microfluidics, time-lapsed single-molecule microscopy and automated image analysis allowing for the observation of an excess of 3000 complete cell cycles of exponentially growing Escherichia coli cells per experiment. The method makes it possible to analyze the rate of gene expression at the level of single proteins
arxiv
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source
The ubiquitin-proteasome system in glioma cell cycle control
Cell Division, 2012 A major determinant of cell fate is regulation of cell cycle. Tight regulation of this process is lost during the course of development and progression of various tumors.
Vlachostergios Panagiotis J +2 more
doaj +1 more source
RELATION OF PROTEIN SYNTHESIS TO THE DIVISION CYCLE IN MAMMALIAN CELL CULTURES [PDF]
, 1963 Edwin W. Taylor
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Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
ESCRT function in cytokinesis: location, dynamics and regulation by mitotic kinases [PDF]
, 2014 Mammalian cytokinesis proceeds by constriction of an actomyosin ring and furrow ingression, resulting in the formation of the midbody bridge connecting two daughter cells. At the centre of the midbody resides the Flemming body, a dense proteinaceous ring
Bhutta, Musab S. +2 more
core +2 more sources
Cell Cycle Arrest is a Conserved Function of Norovirus VPg Proteins
Viruses, 2019 Murine norovirus (MNV) viral protein genome-linked (VPg) manipulates the cell cycle to induce a G0/G1 arrest and gain a beneficial replication environment.
Alice McSweeney +2 more
doaj +1 more source
Protein Turnover in the Cell Cycle of Escherichia coli [PDF]
, 1965 Arasuke Nishi, Tokio Kogoma
openalex +1 more source