Results 261 to 270 of about 10,588,993 (295)
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Role of Cell Cycle Proteins in CNS Injury
Neurochemical Research, 2007Following trauma or ischemia to the central nervous system (CNS), there is a marked increase in the expression of cell cycle-related proteins. This up-regulation is associated with apoptosis of post-mitotic cells, including neurons and oligodendrocytes, both in vitro and in vivo.
Kimberly R, Byrnes, Alan I, Faden
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The retinoblastoma protein and the cell cycle.
Seminars in cancer biology, 1992Although mutations of the retinoblastoma gene (RB1) contribute to malignant progression in many types of tumor, the role of RB1 mutation in cancer initiation is highly restricted to the rare embryonic tumor, retinoblastoma. However, RB1 is expressed and its product, p110RB1, is regulated through the cell cycle in many tissues. This apparent paradox may
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Cell Cycle Regulation by Protein Degradation
2014Cell division is controlled by a highly regulated program to accurately duplicate and segregate chromosomes. An important feature of the cell cycle regulatory program is that key cell cycle proteins are present and active during specific cell cycle stages but are later removed or inhibited to maintain appropriate timing. The ubiquitin-proteasome system
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Science Signaling, 2010
Cyclin D controls gene transcription during mouse retinal development.
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Cyclin D controls gene transcription during mouse retinal development.
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Regulation of transcription by proteins that control the cell cycle
Nature, 1997In eukaryotes, progression of a cell through the cell cycle is partly controlled at the level of transcriptional regulation. Yeast and mammalian cells use similar mechanisms to achieve this regulation. Although gaps still remain, progress has been made recently in connecting the links between the cell's cycle and its transcriptional machinery.
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Cell Cycle Regulation by Protein Kinases and Phosphatases
2001The two main phases of the eukaryotic cell cycle are S phase, when DNA is replicated, and M phase (mitosis), when the duplicated chromosomes are segregated to the two daughter cells. S and M phases are separated by two so-called “gap” phases, G1 (prior to S) and G2 (prior to M), respectively.
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Ratchets and Clocks: The Cell Cycle, Ubiquitylation and Protein Turnover
Nature Reviews Molecular Cell Biology, 2003Steven I Reed
exaly
Cubism and the Cell Cycle: The Many Faces of the APC/C
Nature Reviews Molecular Cell Biology, 2011Jonathon Noe Joseph Pines
exaly