Results 201 to 210 of about 3,307,555 (359)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Flow cytometric phenotyping of diverse human cancer cell lines for immunological biomarkers expression [PDF]

The tumour microenvironment contains a variety of distinct factors that inhibit the immune system and can cause drug resistance. Some of these factors include the expression of cell surface markers which interact directly with immune cells.
Cross, Neil, Hudson, Katie, Jordan-mahy, Nicola, Leyland, Rebecca   +3 more
core  

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

, 1989
Natasha Kyprianou, John T. Isaacs
openalex   +1 more source

Expression of baculovirus P35 prevents cell death in Drosophila [PDF]

, 1994
Bruce A. Hay, Tanya Wolff, Gerald M. Rubin   +2 more
openalex   +1 more source

Cell death rocks [PDF]

Apoptosis, 2019
Griffioen, Arjan W., Nowak-Sliwinska, Patrycja   +1 more
openaire   +4 more sources

A decade of Discovery: celebrating 10 years of Cell Death Discovery. [PDF]

Cell Death Discov
Amelio I.
europepmc   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Cuproptosis and cuproptosis-related cell death and genes: mechanistic links to spermatogenic cell death. [PDF]

Cell Death Discov
Li J, Li N, Wang H, Li B, Tang X, Guan Y, Yang F, Li G, Dong L, Yuan R, Yu X.   +10 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity. [PDF]

, 1991
Anna Batistatou, Lloyd A. Greene
openalex   +1 more source