Results 141 to 150 of about 2,690,374 (356)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Differentiation of a nerve cell [PDF]

, 1989
Anderson, Peter A.V., David, Charles N., Hobmayer, Engelbert   +2 more
core   +1 more source

LOSS OF DIFFERENTIATING NEMATOCYTES INDUCED BY REGENERATION AND WOUND HEALING IN HYDRA [PDF]

, 1984
Cell death was observed in the nematocyte differentiation pathway in Hydra during head and foot regeneration. This death occurs throughout the regenerating piece, is transient in nature and is selective for committed stenotele and desmoneme precursors ...
David, Charles N., Fujisawa, Toshitaka
core  

Can Human Oral Mucosa Stem Cells Differentiate to Corneal Epithelia? [PDF]

, 2021
Sònia López, Lía Hoz, Eda Patricia Tenorio, Beatriz Buentello‐Volante, Fátima Sofía Magaña‐Guerrero, Ana Wintergerst, Alejandro Navas, Yonathan Garfias, Higinio Arzate   +8 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Severe Muscle Deconditioning Triggers Early Extracellular Matrix Remodeling and Resident Stem Cell Differentiation into Adipocytes in Healthy Men [PDF]

, 2022
Corentin Guilhot, Théo Fovet, Pierre Delobel, Manon Dargegen, Bernard J. Jasmin, Thomas Brioche, Angèle Chopard, Guillaume Py   +7 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

SWITCHER, a CRISPR-inducible floxed wild-type Cre regulating CRISPR activity

Communications Biology
Although several Cre-regulated CRISPR/Cas platforms exist, a CRISPR/Cas-controlled Cre-system remains a challenge. Here, we present a genetic switch we term SWITCHER based on a floxed wild-type Cre-construct representing a CRISPR-inducible and self ...
Björn Schuster, Ivana Dobiášovská, Jovana Ćurčić, Petr Pajer, Šimon Borna, Petr Bartůněk   +5 more
doaj   +1 more source

Effects of Low-Concentration Graphene Oxide Quantum Dots on Improving the Proliferation and Differentiation Ability of Bone Marrow Mesenchymal Stem Cells through the Wnt/β-Catenin Signaling Pathway

, 2022
Duoling Xu, Chao Wang, Jie Wu, Yuan-Xiang Fu, Shujun Li, Wentao Hou, Ling Lin, Pei Li, Dongsheng Yu, Wei Zhao   +9 more
openalex   +1 more source

Osteogenic Differentiation of Human Mesenchymal Stem Cells Modulated by Surface Manganese Chemistry in SLA Titanium Implants [PDF]

, 2022
Jin‐Woo Park, Yusuke Tsutsumi, Eui Kyun Park   +2 more
openalex   +1 more source