Results 171 to 180 of about 12,907,435 (362)

T cell receptor signalling in the control of regulatory T cell differentiation and function

Nature reviews. Immunology, 2016
Ming O. Li, A. Rudensky
semanticscholar   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Regulation of revival stem cell differentiation by CREPT/RPRD1B during intestinal regeneration. [PDF]

Cell Biosci
Lan T, Li M, Duan X, Jia H, Cao Y, Wang Y, Ren F, Sheng J, Xu J, Chang Z.   +9 more
europepmc   +1 more source

Simultaneous synthesis of DNA and specialized cellular products by differentiating cartilage cells in vitro. [PDF]

, 1967
Robert D. Cahn, Robert S. Lasher
openalex   +1 more source

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Nature, 2012
Chao Lu, P. Ward, G. Kapoor, D. Rohle, Şevin Turcan, O. Abdel-Wahab, C. Edwards, R. Khanin, M. Figueroa, A. Melnick, K. Wellen, D. O’Rourke, S. Berger, T. Chan, R. Levine, I. Mellinghoff, C. Thompson   +16 more
semanticscholar   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Confined Migration Drives Stem Cell Differentiation. [PDF]

Adv Sci (Weinh)
Gao X, Li Y, Lee JWN, Zhou J, Rangaraj V, Marlena J, Holle AW.   +6 more
europepmc   +1 more source

REQUIREMENT FOR CONTINUOUS ANTIGENIC STIMULATION IN THE DEVELOPMENT AND DIFFERENTIATION OF ANTIBODY-FORMING CELLS [PDF]

, 1969
Michael G. Hanna, Paul Nettesheim, Mary W. Francis   +2 more
openalex   +1 more source

Epigenomics of human CD8 T cell differentiation and aging

Science immunology, 2017
David M. Moskowitz, David W. Zhang, Bin Hu, S. Le Saux, R. Yanes, Zhongde Ye, Jason D. Buenrostro, C. Weyand, W. Greenleaf, J. Goronzy   +9 more
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source