Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis. [PDF]
Hawkins MR +5 more
europepmc +1 more source
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
The intrinsic dimension of gene expression during cell differentiation. [PDF]
Biondo M +5 more
europepmc +1 more source
Development of novel microcarriers for adipose derived stem cell material directed differentiation and expansion [PDF]
Claire L. Gibson
openalex
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Discovery of a chemical small molecule inducing umbilical cord mesenchymal stem cell differentiation to vascular endothelial cells. [PDF]
Zhou B +6 more
europepmc +1 more source
Value of four-dimensional computed tomography angiography combined with stromal cell-derived factor-1 for differentiating ruptured intracranial aneurysms and assessing risk of ruptures [PDF]
Yiming Xu, Chengde Liao
openalex +1 more source
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source
Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation. [PDF]
Coux RX +6 more
europepmc +1 more source

