Results 251 to 260 of about 2,657,787 (357)

The Structural Differentiation of the Alveolar Lining Cells I. Electron Microscopic Studies on the Prospective Alveolar Epithelium in the Lung Tissue of Rat Embryos

, 1966
Yasunosuke Suzuki
openalex   +2 more sources

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Preface of the special issue "Mechanisms of reprogramming for cell differentiation and tissue regeneration". [PDF]

Regen Ther
Shiota G.
europepmc   +1 more source

STUDIES ON THE VARIETAL DIFFERENTIATION OF FROST RESISTANCE OF THE TEA PLANT : VI. The Distribution of Sugars in Cells during Frost Hardening in the Tea Plant with Special Reference to Histochemical Observation by using <14><SUP>C</SUP>-sucrose

, 1968
Noriko Sugiyama, Takashi Shimura
openalex   +2 more sources

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

The protein-tyrosine phosphatase Shp2 is essential for lymphatic endothelial cell differentiation in zebrafish

Woutersen DT, van Impel A, Schulte-Merker S, den Hertog J.   +3 more
europepmc   +1 more source

STUDIES ON THE VARIETAL DIFFERENTIATION OF FROST RESISTANCE OF THE TEA PLANT : VII. The Histochemical Observation of Amylase and Phosphorylase of Cortical Cells of Different Frost Resistance of the Varieties

, 1969
Noriko Sugiyama, Takashi Shimura
openalex   +2 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

The impact of NF-κB2 mutations on Tfh cell differentiation and their critical role in immune function. [PDF]

Transl Pediatr
Chen Y, Zhou W, Li L, Chen T, Wu Q, Li Q, Zhou Y, Qian L.   +7 more
europepmc   +1 more source