Results 261 to 270 of about 2,657,787 (357)

CYTOCHEMICAL STUDIES ON THE PROLIFERATION AND DIFFERENTIATION OF EXPERIMENTAL CHLOROMA CELLS

, 1969
Yoshitake TANAKA
openalex   +2 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

GlyT1 inhibition by ALX-5407 attenuates allograft rejection through suppression of Th1 cell differentiation. [PDF]

Front Immunol
Zhang X, Zhang W, Wei J, Jin S, Wang Z, Wang H, Feng G, Zhao J.   +7 more
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Case report: Bladder carcinoma with shadow cell differentiation: a case report with immunohistochemical analyses. [PDF]

Int J Surg Case Rep
Jouini R, Guesmi I, Helal I, Thayer MB, Oueslati MA, Chadli-Debbiche A.   +5 more
europepmc   +1 more source

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

PML is crucial for neural stem cell differentiation, stress tolerance and mitochondrial integrity. [PDF]

Stem Cell Reports
Spanou S, Makatounakis T, Deligianni E, Papanikolaou S, Samiotaki M, Moretto F, Nikolaou C, Papamatheakis J, Kretsovali A.   +8 more
europepmc   +1 more source

Assembly of the sarcoplasmic reticulum proteins in differentiating rat skeletal muscle cell cultures: localization by immunofluorescence of sarcoplasmic reticulum proteins in differentiating rat skeletal muscle cell cultures

, 1977
AO Jorgensen, Kalnins Vi, E Zubrzyca, MacLennan Dh   +3 more
openalex   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Directing stem cell differentiation by chromatin state approximation

Montano-Gutierrez LF, Müller S, Kutschat AP, Seruggia D, Halbritter F.   +4 more
europepmc   +1 more source