Results 71 to 80 of about 1,775,572 (317)

COMMITMENT DURING NEMATOCYTE DIFFERENTIATION IN HYDRA [PDF]

, 1981
Nematocytes in Hydra differentiate from interstitial stem cells. Desmonemes differentiate mainly in the distal half of the body column while stenoteles differentiate predominantly in the proximal half.
Fujisawa, Toshitaka, David, Charles N.
core  

Stem cell mechanobiology

, 2010
Stem cells are undifferentiated cells that are capable of proliferation, self-maintenance and differentiation towards specific cell phenotypes. These processes are controlled by a variety of cues including physicochemical factors associated with the ...
Jonathan J. Campbell, Martin M. Knight, Dan L. Bader, David A. Lee, Lee, David A., Knight, Martin M., Bader, Dan L., Campbell, Jonathan J.   +7 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation

, 2009
We show that Indian Hedgehog (Ihh) regulates T-cell development and homeostasis in both fetal and adult thymus, controlling thymocyte number. Fetal Ihh-/- thymi had reduced differentiation to double-positive (DP) cell and reduced cell numbers compared ...
Outram, Susan V, Ross, Susan E, Rowbotham, Nicola J, Crompton, T, Hager-Theodorides, Ariadne L, Shah, DK, Shah, Divya K, Drakopoulou, Ekati, Lanske, Beate, Crompton, Tessa, Dessens, Johannes T, Drakopoulou, E, Rowbotham, NJ, Dessens, JT, Ross, SE, Lanske, B, Outram, SV, Hager-Theodorides, AL   +17 more
core   +1 more source

FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal [PDF]

, 2012
Drosophila neuroblasts (NBs) have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type-specific gene expression data.
Jonas Steinmann, Heinrich Reichert, Reichert, Heinrich, Maria Novatchkova, Burkard, Thomas R., Laurenson, Anne-Sophie, Anne-Sophie Laurenson, Knoblich, Juergen A., Steinmann, Jonas, van der Horst, Suzanne, Berger, Christian, Novatchkova, Maria, Christian Berger, Juergen A. Knoblich, Thomas R. Burkard, Heike Harzer, Suzanne van der Horst, Harzer, Heike   +17 more
core   +1 more source

Cell cycle: To differentiate or not to differentiate? [PDF]

Current Biology, 2000
Developmental regulation of the cell cycle is an important determinant of tissue size and shape. Equally important is regulated withdrawal from the cell cycle to allow cells to differentiate. Recent evidence supports a direct link between transcriptional regulation of the cell cycle machinery and cell differentiation.
Myster, Denise L, Duronio, Robert J
openaire   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reliable reference genes for expression analysis of proliferating and adipogenically differentiating human adipose stromal cells

Cellular & Molecular Biology Letters, 2019
Background The proliferation and adipogenic differentiation of adipose stromal cells (ASCs) are complex processes comprising major phenotypical alterations driven by up- and downregulation of hundreds of genes.
Claudia Krautgasser, Markus Mandl, Florian M. Hatzmann, Petra Waldegger, Monika Mattesich, Werner Zwerschke   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization [PDF]

, 2012
Embryonic stem cells derived from nuclear transfer embryos (ntESCs) are particularly valuable for regenerative medicine, as they are a patient-specific and histocompatible cell source for the treatment of varying diseases.
Julianna Kobolak, Ruttachuk Rungsiwiwut, Andras Dinnyes, Mamo, Solomon, Ujhelly, Olga, Csonka, Erika, Solomon Mamo, Hadlaczky, Gyula, Olga Ujhelly, Gyula Hadlaczky, Kobolak, Julianna, Dinnyes, Andras, Erika Csonka, Rungsiwiwut, Ruttachuk   +13 more
core   +1 more source