Results 61 to 70 of about 13,269,236 (369)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle
Cell Division, 2012 Background The clonal transmission of lineage-specific DNA methylation patterns in a mammalian genome during the cellular division is a crucial biological process controlled by the DNA methyltransferase Dnmt1, mainly.
Hervouet Eric +4 more
doaj +1 more source
LocZ Is a New Cell Division Protein Involved in Proper Septum Placement in Streptococcus pneumoniae
mBio, 2014 How bacteria control proper septum placement at midcell, to guarantee the generation of identical daughter cells, is still largely unknown. Although different systems involved in the selection of the division site have been described in selected species,
Nela Holečková +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
Preventing DNA over-replication: a Cdk perspective
Cell Division, 2008 The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis.
Porter Andrew CG
doaj +1 more source
Effects of cell cycle noise on excitable gene circuits [PDF]
, 2016 We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect ...
Bennett, Matthew R. +4 more
core +3 more sources
Stochastic stem cell models with mutation: A comparison of asymmetric and symmetric divisions [PDF]
arXiv, 2020 In order to fulfill cell proliferation and differentiation through cellular hierarchy, stem cells can undergo either asymmetric or symmetric divisions. Recent studies pay special attention to the effect of different modes of stem cell division on the lifetime risk of cancer, and report that symmetric division is more beneficial to delay the onset of ...
arxiv
Mathematical modeling of heterogeneous stem cell regeneration: from cell division to Waddington's epigenetic landscape [PDF]
arXiv, 2023 Stem cell regeneration is a crucial biological process for most self-renewing tissues during the development and maintenance of tissue homeostasis. In developing the mathematical models of stem cell regeneration and tissue development, cell division is the core process connecting different scale biological processes and leading to changes in cell ...
arxiv
FEBS Letters, EarlyView.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Mitofusin 1 is degraded at G2/M phase through ubiquitylation by MARCH5
Cell Division, 2012 Background Mitochondria exhibit a dynamic morphology in cells and their biogenesis and function are integrated with the nuclear cell cycle. In mitotic cells, the filamentous network structure of mitochondria takes on a fragmented form.
Park Yong-Yea, Cho Hyeseong
doaj +1 more source