Results 1 to 10 of about 689,015 (351)

Compartmentalized cell envelope biosynthesis in Mycobacterium tuberculosis [PDF]

mBio
The inner membrane domain (IMD) is a metabolically active and laterally discrete membrane domain initially discovered in Mycobacterium smegmatis. The IMD correlates both temporally and spatially with the polar cell envelope elongation in M.
Julia Puffal, Ian L. Sparks, James R. Brenner, Xuni Li, John D. Leszyk, Jennifer M. Hayashi, Scott A. Shaffer, Yasu S. Morita   +7 more
doaj   +2 more sources

The Pseudomonas aeruginosa Cpx system provides a cyclic-di-GMP independent link between cell envelope stress and surface sensing [PDF]

mBio
Bacteria surveil their cell envelope through a network of envelope stress response systems (ESRs). Beyond regulation of envelope maintenance, ESRs influence expression of a range of virulence traits among pathogenic bacteria. The Cpx two-component system,
Megan R. O'Malley, Hailey N. Dearing, Xuhui Zheng, Alyssa N. Kretschmer, Timothy H.-S. Cho, Tracy L. Raivio, Matthew R. Parsek   +6 more
doaj   +2 more sources

Molecular interplay between peptidoglycan integrity and outer membrane asymmetry in maintaining cell envelope homeostasis [PDF]

Journal of Bacteriology
The bacterial cell envelope is a critical interface with the environment, particularly in Gram-negative species where the outer membrane (OM) and peptidoglycan (PG) layers coordinate to maintain structural integrity and resist turgor.
Sinjini Nandy, Arshya F. Tehrani, Augusto C. Hunt-Serracin, Jacob Biboy, Christine Pybus, Waldemar Vollmer, Joseph M. Boll   +6 more
doaj   +2 more sources

Two-Component MprAB System Regulates the Expression of Genes Involved in Cell Envelope Biosynthesis in Corynebacterium glutamicum [PDF]

Microorganisms
To accurately detect internal and environmental cues, bacteria have evolved signal transduction pathways such as two-component systems (TCSs) to reprogram appropriate genetic and physiological functions for adaptation and survival.
Yu Zou, Danni Huang, Xiuxia Liu, Yankun Yang, Chunli Liu, Ye Li, Zhonghu Bai   +6 more
doaj   +2 more sources

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth.

PLoS Genetics, 2021
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrates within a confined space while providing a protective barrier to the external environment. Destabilising the envelope of bacterial pathogens is a common
Emily C A Goodall, Georgia L Isom, Jessica L Rooke, Karthik Pullela, Christopher Icke, Zihao Yang, Gabriela Boelter, Alun Jones, Isabel Warner, Rochelle Da Costa, Bing Zhang, James Rae, Wee Boon Tan, Matthias Winkle, Antoine Delhaye, Eva Heinz, Jean-Francois Collet, Adam F Cunningham, Mark A Blaskovich, Robert G Parton, Jeff A Cole, Manuel Banzhaf, Shu-Sin Chng, Waldemar Vollmer, Jack A Bryant, Ian R Henderson   +25 more
doaj   +1 more source

Detection of Mycobacterium avium Subspecies paratuberculosis (MAP) Microorganisms Using Antigenic MAP Cell Envelope Proteins

Frontiers in Veterinary Science, 2021
Cell envelope proteins from Mycobacterium avium subspecies paratuberculosis (MAP) that are antigenically distinct from closely related mycobacterial species are potentially useful for Johne's Disease (JD) diagnosis.
Shanmugasundaram Karuppusamy, Lucy Mutharia, David Kelton, Brandon Plattner, Sanjay Mallikarjunappa, Niel Karrow, Gordon Kirby   +6 more
doaj   +1 more source

Anti-tuberculosis drug development via targeting the cell envelope of Mycobacterium tuberculosis

Frontiers in Microbiology, 2022
Mycobacterium tuberculosis possesses a dynamic cell envelope, which consists of a peptidoglycan layer, a mycolic acid layer, and an arabinogalactan polysaccharide.
Xinyue Xu, Baoyu Dong, Lijun Peng, Chao Gao, Chao Gao, Zhiqun He, Chuan Wang, Jumei Zeng   +7 more
doaj   +1 more source

Co-ordinated assembly of the multilayered cell envelope of Gram-negative bacteria. [PDF]

Curr Opin Microbiol
Fivenson EM, Dubois L, Bernhardt TG.
europepmc   +2 more sources

The NtrYX Two-Component System Regulates the Bacterial Cell Envelope

mBio, 2020
Activity of the NtrYX two-component system has been associated with important processes in diverse bacteria, ranging from symbiosis to nitrogen and energy metabolism.
Kimberly C. Lemmer, François Alberge, Kevin S. Myers, Alice C. Dohnalkova, Ryan E. Schaub, Jonathan D. Lenz, Saheed Imam, Joseph P. Dillard, Daniel R. Noguera, Timothy J. Donohue   +9 more
doaj   +1 more source

Genome-Wide Identification of Pseudomonas aeruginosa Genes Important for Desiccation Tolerance on Inanimate Surfaces

mSystems, 2022
Pseudomonas aeruginosa is an opportunistic pathogen prevalent in the environment and in health care settings. Transmission in the health care setting occurs through human-human interactions and/or contact with contaminated surfaces.
Sardar Karash, Timothy L. Yahr
doaj   +1 more source