Results 11 to 20 of about 374,821 (162)

The Phospholipid N-Methyltransferase and Phosphatidylcholine Synthase Pathways and the ChoXWV Choline Uptake System Involved in Phosphatidylcholine Synthesis Are Widely Conserved in Most, but Not All Brucella Species

open access: yesFrontiers in Microbiology, 2021
The brucellae are facultative intracellular bacteria with a cell envelope rich in phosphatidylcholine (PC). PC is abundant in eukaryotes but rare in prokaryotes, and it has been proposed that Brucella uses PC to mimic eukaryotic-like features and avoid ...
Beatriz Aragón-Aranda   +13 more
doaj   +1 more source

MacP bypass variants of Streptococcus pneumoniae PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases

open access: yesmBio, 2023
The peptidoglycan (PG) layer protects bacteria from osmotic lysis and defines their shape. The class A penicillin-binding proteins (aPBPs) are PG synthases that possess both glycan polymerization and crosslinking activities needed for PG biogenesis.
Caroline Midonet   +5 more
doaj   +1 more source

The Gram-negative permeability barrier: tipping the balance of the in and the out

open access: yesmBio, 2023
Gram-negative bacteria are intrinsically resistant to many antibiotics, due in large part to the permeability barrier formed by their cell envelope. The complex and synergistic interplay of the two Gram-negative membranes and active efflux prevents the ...
Claire Maher, Karl A. Hassan
doaj   +1 more source

Cell Envelope Modifications Generating Resistance to Hop Beta Acids and Collateral Sensitivity to Cationic Antimicrobials in Listeria monocytogenes

open access: yesMicroorganisms, 2023
Hop beta acids (HBAs) are characteristic compounds from the hop plant that are of interest for their strong antimicrobial activity. In this work, we report a resistance mechanism against HBA in the foodborne pathogen Listeria monocytogenes.
Maarten Goedseels, Chris W. Michiels
doaj   +1 more source

Cell entry of enveloped viruses [PDF]

open access: yesCurrent Opinion in Virology, 2011
Infection of cells by enveloped viruses requires merger of the viral envelope membrane with target cell membranes, resulting in the formation of fusion pores through which the viral genome is released. Since lipid membranes do not mix spontaneously, the fusion process is energy-dependent and mediated by viral envelope glycoprotein complexes.
François-Loïc, Cosset   +1 more
openaire   +6 more sources

Detection of Mycobacterium avium Subspecies paratuberculosis (MAP) Microorganisms Using Antigenic MAP Cell Envelope Proteins

open access: yesFrontiers in Veterinary Science, 2021
Cell envelope proteins from Mycobacterium avium subspecies paratuberculosis (MAP) that are antigenically distinct from closely related mycobacterial species are potentially useful for Johne's Disease (JD) diagnosis.
Shanmugasundaram Karuppusamy   +6 more
doaj   +1 more source

BonA from Acinetobacter baumannii Forms a Divisome-Localized Decamer That Supports Outer Envelope Function

open access: yesmBio, 2021
Acinetobacter baumannii is a high-risk pathogen due to the rapid global spread of multidrug-resistant lineages. Its phylogenetic divergence from other ESKAPE pathogens means that determinants of its antimicrobial resistance can be difficult to ...
Rhys Grinter   +13 more
doaj   +1 more source

The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance

open access: yesMicroorganisms, 2020
Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and ...
Alice Chateau   +3 more
doaj   +1 more source

Exogenous and Endogenous Phosphoethanolamine Transferases Differently Affect Colistin Resistance and Fitness in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2021
Colistin represents a last-line treatment option for infections caused by multidrug resistant Gram-negative pathogens, including Pseudomonas aeruginosa.
Matteo Cervoni   +5 more
doaj   +1 more source

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth.

open access: yesPLoS Genetics, 2021
The cell envelope is essential for viability in all domains of life. It retains enzymes and substrates within a confined space while providing a protective barrier to the external environment. Destabilising the envelope of bacterial pathogens is a common
Emily C A Goodall   +25 more
doaj   +1 more source

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