Results 31 to 40 of about 374,821 (162)

Anti-tuberculosis drug development via targeting the cell envelope of Mycobacterium tuberculosis

open access: yesFrontiers in Microbiology, 2022
Mycobacterium tuberculosis possesses a dynamic cell envelope, which consists of a peptidoglycan layer, a mycolic acid layer, and an arabinogalactan polysaccharide.
Xinyue Xu   +7 more
doaj   +1 more source

Genome-Wide Identification of Pseudomonas aeruginosa Genes Important for Desiccation Tolerance on Inanimate Surfaces

open access: yesmSystems, 2022
Pseudomonas aeruginosa is an opportunistic pathogen prevalent in the environment and in health care settings. Transmission in the health care setting occurs through human-human interactions and/or contact with contaminated surfaces.
Sardar Karash, Timothy L. Yahr
doaj   +1 more source

An inhibitor/anti-inhibitor system controls the activity of lytic transglycosylase MltF in Pseudomonas aeruginosa

open access: yesmBio, 2023
Most bacterial cell envelopes contain a cell wall layer made of peptidoglycan. The synthesis of new peptidoglycan is critical for cell growth, division, and morphogenesis and is also coordinated with peptidoglycan hydrolysis to accommodate the new ...
Michelle Wang   +2 more
doaj   +1 more source

The Mycobacterial Cell Envelope--Lipids [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
Mycobacterium tuberculosis (Mtb) lipids are indelibly imprinted in just about every key aspect of tuberculosis (TB) basic and translational research. Although the interest in these compounds originally stemmed from their abundance, structural diversity, and antigenicity, continued research in this field has been driven by their important contribution ...
openaire   +2 more sources

Activation of the Extracytoplasmic Function σ Factor σP by β-Lactams in Bacillus thuringiensis Requires the Site-2 Protease RasP

open access: yesmSphere, 2019
Bacteria can utilize alternative σ factors to regulate sets of genes in response to changes in the environment. The largest and most diverse group of alternative σ factors are the extracytoplasmic function (ECF) σ factors.
Theresa D. Ho   +3 more
doaj   +1 more source

Genome-wide identification of novel genes involved in Corynebacteriales cell envelope biogenesis using Corynebacterium glutamicum as a model.

open access: yesPLoS ONE, 2020
Corynebacteriales are Actinobacteria that possess an atypical didermic cell envelope. One of the principal features of this cell envelope is the presence of a large complex made up of peptidoglycan, arabinogalactan and mycolic acids.
Célia de Sousa-d'Auria   +4 more
doaj   +1 more source

The cell-envelope glycolipids of baker's yeast [PDF]

open access: yesBiochemical Journal, 1974
Sphingolipids were found to dominate in the glycolipids from the cell envelope of baker's yeast. A relatively large quantity of ceramides was detected. Among the several complex phosphosphingolipids described, ceramide-(P-inositol)2-mannose was the main component.
K, Työrinoja   +2 more
openaire   +2 more sources

Loss of Bacterial Cell Pole Stabilization in Caulobacter crescentus Sensitizes to Outer Membrane Stress and Peptidoglycan-Directed Antibiotics

open access: yesmBio, 2020
Rod-shaped bacteria frequently localize proteins to one or both cell poles in order to regulate processes such as chromosome replication or polar organelle development.
Simon-Ulysse Vallet   +8 more
doaj   +1 more source

Synthesis and recycling of the mycobacterial cell envelope

open access: yesCurrent Opinion in Microbiology, 2021
Mycobacterium tuberculosis (Mtb), the causative agent of the disease tuberculosis, is a recognised global health concern. The efficacy of the current treatment regime is under threat due to the emergence of antibiotic resistance, directing an urgent requirement for the discovery of new anti-tubercular agents and drug targets.
Abrahams, Katherine A, Besra, Gurdyal S
openaire   +2 more sources

A mutant Escherichia coli that attaches peptidoglycan to lipopolysaccharide and displays cell wall on its surface

open access: yeseLife, 2014
The lipopolysaccharide (LPS) forms the surface-exposed leaflet of the outer membrane (OM) of Gram-negative bacteria, an organelle that shields the underlying peptidoglycan (PG) cell wall.
Marcin Grabowicz   +5 more
doaj   +1 more source

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