Results 1 to 10 of about 374,821 (162)
The NtrYX Two-Component System Regulates the Bacterial Cell Envelope
mBio, 2020 Activity of the NtrYX two-component system has been associated with important processes in diverse bacteria, ranging from symbiosis to nitrogen and energy metabolism.
Kimberly C. Lemmer +9 more
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Compartmentalized cell envelope biosynthesis in Mycobacterium tuberculosis [PDF]
mBioThe inner membrane domain (IMD) is a metabolically active and laterally discrete membrane domain initially discovered in Mycobacterium smegmatis. The IMD correlates both temporally and spatially with the polar cell envelope elongation in M.
Julia Puffal +7 more
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The Pseudomonas aeruginosa Cpx system provides a cyclic-di-GMP independent link between cell envelope stress and surface sensing [PDF]
mBioBacteria surveil their cell envelope through a network of envelope stress response systems (ESRs). Beyond regulation of envelope maintenance, ESRs influence expression of a range of virulence traits among pathogenic bacteria. The Cpx two-component system,
Megan R. O'Malley +6 more
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A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance
Applied Sciences, 2023 Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
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Annual Review of Microbiology, 2023 The cell envelope is a multilayered structure that insulates the interior of bacterial cells from an often chaotic outside world. Common features define the envelope across the bacterial kingdom, but the molecular mechanisms by which cells build and regulate this critical barrier are diverse and reflect the evolutionary histories of bacterial lineages.
Alakavuklar, Melene A. +2 more
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A Biological Signature for the Inhibition of Outer Membrane Lipoprotein Biogenesis
mBio, 2022 The outer membrane (OM) of Gram-negative bacteria is an essential organelle that acts as a formidable barrier to antibiotics. Increasingly prevalent resistance to existing drugs has exacerbated the need for antibiotic discovery efforts targeting the OM ...
Kelly M. Lehman +2 more
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mBio, 2022 Pyrazinamide (PZA) plays a crucial role in first-line tuberculosis drug therapy. Unlike other antimicrobial agents, PZA is active against Mycobacterium tuberculosis only at low pH. The basis for this conditional drug susceptibility remains undefined.
Joshua M. Thiede +8 more
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The Bacterial Cell Envelope [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 The bacteria cell envelope is a complex multilayered structure that serves to protect these organisms from their unpredictable and often hostile environment. The cell envelopes of most bacteria fall into one of two major groups. Gram-negative bacteria are surrounded by a thin peptidoglycan cell wall, which itself is surrounded by an outer membrane ...
Thomas J, Silhavy +2 more
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Journal of Fungi, 2022 Acetic acid is a major inhibitory compound in several industrial bioprocesses, in particular in lignocellulosic yeast biorefineries. Cell envelope remodeling, involving cell wall and plasma membrane composition, structure and function, is among the ...
Ricardo A. Ribeiro +6 more
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Viral Ejection Proteins: Mosaically Conserved, Conformational Gymnasts
Microorganisms, 2022 Bacterial viruses (or bacteriophages) have developed formidable ways to deliver their genetic information inside bacteria, overcoming the complexity of the bacterial-cell envelope. In short-tailed phages of the Podoviridae superfamily, genome ejection is
Nicholas A. Swanson +2 more
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