Results 11 to 20 of about 5,408,362 (316)
WIREs Systems Biology and Medicine, 2019 AbstractCell fate decisions are controlled by complex intracellular molecular regulatory networks. Studies increasingly reveal the scale of this complexity: not only do cell fate regulatory networks contain numerous positive and negative feedback loops, they also involve a range of different kinds of nonlinear protein–protein and protein–DNA ...
Michael J. Casey +2 more
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Cell Cycle, 2016 Shapes of the cell have fascinated our curiosity since the discovery of the cell by Robert Hooke in 16651 and by Anton van Leeuwenhoek slightly later2 using the state-of-the-art microscopes of the ...
Sato, T.N. (Thomas N.) +1 more
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Birth Defects Research Part C: Embryo Today: Reviews, 2009 AbstractDiabetes is characterized by decreased function of insulin‐producing β cells and insufficient insulin output resulting from an absolute (Type 1) or relative (Type 2) inadequate functional β cell mass. Both forms of the disease would greatly benefit from treatment strategies that could enhance β cell regeneration and/or function.
Michelle A, Guney, Maureen, Gannon
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Stochasticity and Cell Fate [PDF]
Science, 2008 Fundamental to living cells is the capacity to differentiate into subtypes with specialized attributes. Understanding the way cells acquire their fates is a major challenge in developmental biology. How cells adopt a particular fate is usually thought of as being deterministic, and in the large majority of cases it is. That is, cells acquire their fate
Richard, Losick, Claude, Desplan
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BTG interacts with retinoblastoma to control cell fate in Dictyostelium. [PDF]
, 2010 In the genesis of many tissues, a phase of cell proliferation is followed by cell cycle exit and terminal differentiation. The latter two processes overlap: genes involved in the cessation of growth may also be important in triggering differentiation ...
Adriano Ceccarelli +9 more
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Stem cell decisions:A twist of fate or a niche market? [PDF]
, 2014 Establishing and maintaining cell fate in the right place at the right time is a key requirement for normal tissue maintenance. Stem cells are at the core of this process.
Näthke, Inke +3 more
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smurph50/cell-fate-and-reprogramming-scatac-seq: code
, 2023 Using single cell ATAC-seq to analyze siRNA knockdown of novel cell fate regulators in fibroblasts reprogrammed to ...
Sean Murphy
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The Fate of Human Treg Cells [PDF]
Immunity, 2009 In this issue of Immunity, Miyara et al. (2009) demonstrate that FoxP3(+) cells in human peripheral blood are heterogeneous in function, and CD45RA expression defines their different stages of differentiation.
BATTAGLIA, MARCO MARIA +1 more
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Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine [PDF]
, 2010 Coordination between cell fate specification and cell cycle control in multicellular organisms is essential to regulate cell numbers in tissues and organs during development, and its failure may lead to oncogenesis.
Segref, Alexandra +9 more
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Nature Reviews Neuroscience, 2018 Progressive hyperpolarization of ventricular zone progenitors regulates their sequential differentiation and migration in mouse primary sensory cortex.
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