Results 81 to 90 of about 12,578,619 (347)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

Nature Communications, 2018
The liver is the largest solid organ in the body and is critical for metabolic and immune functions. However, little is known about the cells that make up the human liver and its immune microenvironment.
S. Macparland, Jeffrey C. Liu, Xuezhong Ma, Brendan T. Innes, A. Bartczak, B. K. Gage, J. Manuel, Nicholas Khuu, J. Echeverri, I. Linares, Rahul Gupta, Michael L Cheng, Lewis Y. Liu, Damra Camat, Sai W. Chung, Rebecca K Seliga, Zigong Shao, Elizabeth Lee, Shinichiro Ogawa, Mina Ogawa, M. Wilson, Jason E. Fish, M. Selzner, A. Ghanekar, D. Grant, P. Greig, G. Sapisochin, N. Selzner, N. Winegarden, O. Adeyi, G. Keller, Gary D Bader, I. McGilvray   +32 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Definitive Radiotherapy in LocallyAdvanced Non-Small Cell Lung Cancer: Dose and Fractionation

Balkan Medical Journal, 2014
Definitive radiotherapy plays a major role in the treatment of locally advanced non-small cell lung cancer (LA NSCLC). After the impact of RT dose for lung cancer was established, a number of trials were structured with the aim of better local control ...
Nergiz Dağoğlu, Şule Karaman, Alptekin Arifoğlu, Seden Küçücük, Ethem N. Oral   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A robust fractionation method for protein subcellular localization studies in Escherichia coli.

BioTechniques, 2019
Fractionation in Gram-negative bacteria is used to identify the subcellular localization of proteins, in particular the localization of exported recombinant proteins.
G. Malherbe, D. Humphreys, E. Davé
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Comparison of Lemi, Lemii and Lemiii to Prediction of Cell Survival Fraction of Htb140 Cell Line with Geant4 and Survival Code in Proton Therapy

, 2023
Roya Barati, A. Attili, Seyed Abdolhadi Hosseinzadeh, Mohammad Nazmabadi   +3 more
openalex   +1 more source

Anti-cancer activity of Carica papaya leaf ethanolic extract and fractions against selected human cancer cell lines [PDF]

, 2023
Pedro Raúl Gutiérrez, A Ahmed, M Kaleem, Ahmed Shafiq, H, E Alorkpa, Nathanie Boadi, N Badu, M Saah, S, W Bandaranayake, C Cerella, M Dicato, M Diederich, L Dawara, C Joshi, R Singh, M Dhanamani, Lakshmi Devi, S Kannan, S, D Dias, Urban, S Roessner, J Doughari, A Elmahmood, S Manzara, P Gutierrez, B Hausteen, S Hayek, R Gyawali, S Ibrahim, H Hewitt, S Whittle, S Lopez, E Bailey, S Weaver, S Kumar, W Lamorte, H Li, Z Wang, Y Liu, J Liu, T Henkel, L Lotufo, M Khan, A Ather, S Louzada, F Adega, R Chaves, J Mattern, M Bak, E Hahn, M Moudi, R Go, C Yien, M Nazre, N Nakatsu, Y Yoshida, K Yamazaki, T Nakamura, S Dan, Y Fukui, T Yamori, T Nguyen, M Parat, P Shaw, A Hewavitharana, M Hodson, T Nobori, K Miurak, D Wu, L Takabayashik, Carson, D Okwu, J Rojas, V Ochoa, S Ocampo, J Muoz, C Schmitt, S Sharma, D Haber, J Settleman, A Thenmozhi, A Nagalakshmi, Mahadeva Rao, U, R Thoppil, A Bishayee, T Vargo-Gogola, J Rosen, I Waheed, M Ahmad, N Syed, R Ashraf, N Yahfoufi, N Alsadi, M Jambi, C Matar, K Zeng   +99 more
openalex   +1 more source