Results 31 to 40 of about 12,032,873 (351)
Selective cell fusion is a natural part of development. It is found in sexually reproducing organisms that require fertilization to propagate and in muscles, placenta, bones, lens of the eye and stem cells. Cell fusion is particularly important in the development of C. elegans: in addition to 300 sperm and oocytes that fuse during fertilization, 300 of
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Cell fusion and plasticity [PDF]
Cell plasticity is a central issue in stem cell biology. In many recent discussions, observation of cell fusion has been seen as a confounding factor which calls into question published results concerning cell plasticity of, particularly, adult stem cells.
Joseph J, Lucas, Naohiro, Terada
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Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.
Kaori Iwai +4 more
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Current status of biotechnology in China
There has been increasing interest over past decade in exploring the possibility of using new biotechinology to produce new products and to improve the old productive process.
Sheng-Li Yang
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Cancer cell–immune cell hybrids and cancer immunotherapy have attracted much attention in recent years. The design of efficient cell pairing and fusion chips for hybridoma generation has been, subsequently, a subject of great interest.
Gaurav Pendharkar +6 more
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Summary: Circadian rhythms regulate cell proliferation and differentiation; however, little is known about their roles in myogenic differentiation. Our synchronized differentiation studies demonstrate that myoblast proliferation and subsequent myotube ...
Matthew Lowe +13 more
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Peripheral blood MФ–cancer cell fusion hybrids identified in cancer patients correlate with disease stage and overall survival. High lethality rates associated with metastatic cancer highlight an urgent medical need for improved understanding of biologic
Charles E. Gast +27 more
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Somatic Sex: On the Origin of Neoplasms With Chromosome Counts in Uneven Ploidy Ranges
Stable aneuploid genomes with nonrandom numerical changes in uneven ploidy ranges define distinct subsets of hematologic malignancies and solid tumors. The idea put forward herein suggests that they emerge from interactions between diploid mitotic and G0/
Oskar A. Haas
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TGFβ signaling curbs cell fusion and muscle regeneration
Muscle cell fusion is a multistep process involving cell migration, adhesion, membrane remodeling and actin-nucleation pathways to generate multinucleated myotubes. However, molecular brakes restraining cell–cell fusion events have remained elusive. Here
Francesco Girardi +10 more
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Cell Fusion in Human Cancer: The Dark Matter Hypothesis
Current strategies to determine tumor × normal (TN)-hybrid cells among human cancer cells include the detection of hematopoietic markers and other mesodermal markers on tumor cells or the presence of donor DNA in cancer samples from patients who had ...
J. Weiler, T. Dittmar
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