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The recent pandemic SARS-CoV-2 outbreak affects all kinds of individuals worldwide. The health, social, and economic impacts of the pandemic are dramatic, and vaccines or specific treatment options are not yet available.
Leo Pruimboom, Leo Pruimboom
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Giant cells: multiple cells unite to survive
Multinucleated Giant Cells (MGCs) are specialized cells that develop from the fusion of multiple cells, and their presence is commonly observed in human cells during various infections. However, MGC formation is not restricted to infections alone but can
Shreyasee Hazra+7 more
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In the adult mammalian heart, no data have yet shown the existence of cardiomyocyte-differentiable stem cells that can be used to practically repair the injured myocardium.
Mariko Omatsu-Kanbe+3 more
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Surface activity of cancer cells: the fusion of two cell aggregates [PDF]
Although a good comprehension of how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been generated, the impact of collective migration on cellular rearrangement from subcellular to supracellular level remains less understood.
arxiv
The stochastic entry of enveloped viruses: Fusion vs. endocytosis [PDF]
Viral infection requires the binding of receptors on the target cell membrane to glycoproteins, or ``spikes,'' on the viral membrane. The initial entry is usually classified as fusogenic or endocytotic. However, binding of viral spikes to cell surface receptors not only initiates the viral adhesion and the wrapping process necessary for internalization,
arxiv +1 more source
Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum
Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes (CATs) are significant events during colony establishment in culture and on ...
Smija M. Kurian+2 more
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The First Family of Cell-Cell Fusion [PDF]
Our understanding of the developmentally critical process of cell-cell fusion has been greatly advanced by the identification of the first family of cell-cell fusion proteins. Together, the two founding members of the FF family execute the majority of cell-cell fusion events in C. elegans.
openaire +3 more sources
Not all antibodies against SARS-CoV-2 inhibit viral entry, and hence, infection. Neutralizing antibodies are more likely to reflect real immunity; however, certain tests investigate protein/protein interaction rather than the fusion event.
Fabien Abdul+9 more
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Mechanisms of receptor/coreceptor-mediated entry of enveloped viruses [PDF]
Enveloped viruses enter host cells either through endocytosis, or by direct fusion of the viral membrane envelope and the membrane of the host cell. However, some viruses, such as HIV-1, HSV-1, and Epstein-Barr can enter a cell through either mechanism, with the choice of pathway often a function of the ambient physical chemical conditions, such as ...
arxiv +1 more source
Herpes simplex virus 1 and 2 infections cause high unmet disease burdens worldwide. Mainly HSV-2 causes persistent sexually transmitted disease, fatal neonatal disease and increased transmission of HIV/AIDS.
Ursula A. Gompels+5 more
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