Results 41 to 50 of about 12,032,873 (351)

Tumor Microenvironment and Cell Fusion

open access: yesBioMed Research International, 2019
Cell fusion is a highly regulated biological process that occurs under both physiological and pathological conditions. The cellular and extracellular environment is critical for the induction of the cell–cell fusion.
Erhui Jiang   +3 more
semanticscholar   +1 more source

Mitochondria Donation by Mesenchymal Stem Cells: Current Understanding and Mitochondria Transplantation Strategies

open access: yesFrontiers in Cell and Developmental Biology, 2021
The phenomenon of mitochondria donation is found in various tissues of humans and animals and is attracting increasing attention. To date, numerous studies have described the transfer of mitochondria from stem cells to injured cells, leading to increased
Marina O. Gomzikova   +5 more
doaj   +1 more source

Myeloid cell‐derived tumor necrosis factor‐alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers

open access: yesAging Cell, 2018
Sarcopenia is age‐related muscle wasting that lacks effective therapeutic interventions. We found that systemic ablation of tumor necrosis factor‐α (TNF‐α) prevented sarcopenia and prevented age‐related change in muscle fiber phenotype.
Ying Wang   +3 more
semanticscholar   +1 more source

Normal microspore production after cell fusion in Brachiaria jubata (Gramineae)

open access: yesGenetics and Molecular Biology, 2003
Cytogenetic studies were carried out on 22 accessions of Brachiaria jubata from the Embrapa Beef Cattle Brachiaria collection. One accession was diploid (2n = 2x = 18) and the remaining 21 were tetraploid (2n = 4x = 36). Among five tetraploid accessions,
Andréa Beatriz Mendes-Bonato   +3 more
doaj   +1 more source

Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion

open access: yesThe Journal of General Physiology, 2018
Limb-girdle muscular dystrophy type 2L (LGMD2L) is a myopathy arising from mutations in ANO5; however, information about the contribution of ANO5 to muscle physiology is lacking. To explain the role of ANO5 in LGMD2L, we previously hypothesized that ANO5-
Jarred M. Whitlock   +3 more
semanticscholar   +1 more source

V-fusion: a convenient, nontoxic method for cell fusion

open access: yesBioTechniques, 2010
Cell-to-cell fusion (cell fusion) is a fundamental biological process that also has been used as a versatile experimental tool to dissect a variety of cellular mechanisms, including the consequences of cell fusion itself, and to produce cells with ...
Amy Gottesman   +2 more
doaj   +1 more source

A Cellular Assay for Spike/ACE2 Fusion: Quantification of Fusion-Inhibitory Antibodies after COVID-19 and Vaccination

open access: yesViruses, 2022
Not all antibodies against SARS-CoV-2 inhibit viral entry, and hence, infection. Neutralizing antibodies are more likely to reflect real immunity; however, certain tests investigate protein/protein interaction rather than the fusion event.
Fabien Abdul   +9 more
doaj   +1 more source

Srf controls satellite cell fusion through the maintenance of actin architecture

open access: yesJournal of Cell Biology, 2018
Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here, we show that serum response factor (Srf) is needed for optimal SC-mediated hypertrophic growth. We identified Srf as a master regulator of SC
Voahangy Randrianarison-Huetz   +11 more
semanticscholar   +1 more source

The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner

open access: yesCells, 2020
MacroH2A histone variants have functions in differentiation, somatic cell reprogramming and cancer. However, at present, it is not clear how macroH2As affect gene regulation to exert these functions.
Sarah Hurtado-Bagès   +8 more
doaj   +1 more source

Two cellular models for analyzing mitochondrial heteroplasmy [PDF]

open access: yesExploration of Neuroscience
Aim: Mitochondria are essential for brain development, and the presence of different mitochondrial types is called mitochondrial heteroplasmy. Mitochondrial dysfunction is a central aspect of many people’s neurological diseases.
Yaning Hu   +3 more
doaj   +1 more source

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