Results 41 to 50 of about 12,374,157 (394)
Allergology International, 2007 Background: Osteoclasts are bone-resorbing multinuclear polykaryons essential for bone remodeling, formed through cell fusion of mononuclear macrophage/monocyte lineage precursor cells upon stimulation by the RANK/RANKL system.
Kaori Iwai +4 more
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Giant cells: multiple cells unite to survive
Frontiers in Cellular and Infection Microbiology, 2023 Multinucleated Giant Cells (MGCs) are specialized cells that develop from the fusion of multiple cells, and their presence is commonly observed in human cells during various infections. However, MGC formation is not restricted to infections alone but can
Shreyasee Hazra +7 more
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Science Advances, 2018 Peripheral blood MФ–cancer cell fusion hybrids identified in cancer patients correlate with disease stage and overall survival. High lethality rates associated with metastatic cancer highlight an urgent medical need for improved understanding of biologic
Charles E. Gast +27 more
semanticscholar +1 more source
Current status of biotechnology in China
Memorias do Instituto Oswaldo Cruz, 1991 There has been increasing interest over past decade in exploring the possibility of using new biotechinology to produce new products and to improve the old productive process.
Sheng-Li Yang
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Ca2+ Signalling Differentially Regulates Germ-Tube Formation and Cell Fusion in Fusarium oxysporum
Journal of Fungi, 2022 Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes (CATs) are significant events during colony establishment in culture and on ...
Smija M. Kurian +2 more
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Phagosome-lysosome fusion is a calcium-independent event in macrophages. [PDF]
, 1996 Phagosome-lysosome membrane fusion is a highly regulated event that is essential for intracellular killing of microorganisms. Functionally, it represents a form of polarized regulated secretion, which is classically dependent on increases in ...
Ernst, JD +5 more
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TGFβ signaling curbs cell fusion and muscle regeneration
Nature Communications, 2019 Muscle cell fusion is a multistep process involving cell migration, adhesion, membrane remodeling and actin-nucleation pathways to generate multinucleated myotubes. However, molecular brakes restraining cell–cell fusion events have remained elusive. Here
Francesco Girardi +10 more
semanticscholar +1 more source
A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion
eLife, 2020 Cell-cell fusion, which is essential for tissue development and used by some viruses to form pathological syncytia, is typically driven by fusogenic membrane proteins with tall (>10 nm) ectodomains that undergo conformational changes to bring apposing
Ka Man Carmen Chan +3 more
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Ancestry dependent balancing selection of placental dysferlin at high-altitude
Frontiers in Cell and Developmental Biology, 2023 Introduction: The placenta mediates fetal growth by regulating gas and nutrient exchange between the mother and the fetus. The cell type in the placenta where this nutrient exchange occurs is called the syncytiotrophoblast, which is the barrier between ...
William E. Gundling +5 more
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Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines [PDF]
, 2018 Background: Gene fusions derive from chromosomal rearrangements and the resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with ...
Bolis, Marco +7 more
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