Results 161 to 170 of about 3,364,337 (313)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Spatially-resolved optical monitoring of bioreactor cell growth. [PDF]

Biomed Opt Express
Gorecki J, Redwood-Sawyerr C, Cao J, Dehghani H, Kontoravdi C, Polizzi K, Rowlands C.   +6 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Reversible Nucleolar Stress and Cell Growth Arrest Triggered by Acidic pH. [PDF]

J Cell Physiol
de Mesquita CB, Kaida A, Nojima H, Miura M.   +3 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The MYB-related transcription factor MYPOP acts as a selective regulator of cancer cell growth. [PDF]

Commun Biol
Strunk J, Hüppner A, Sial M, Plath M, Sheriff MB, Wagner S, Freitag K, Mikuličić S, Döring T, Bopp T, Klein M, Rajalingam K, Harms G, Marini F, Nedwed AS, Hankeln T, Osterhof C, Schneider MA, Henrich A, Nubbemeyer A, Suchan M, Brill S, Perkovic M, Schrörs B, Kreiter S, Kölsch A, Diken M, Florin L.   +27 more
europepmc   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Thermosensory reconfiguration of the auxin transcriptional pathway to drive root cell growth. [PDF]

Nat Commun
Borniego MB, Pereyra ME, Sageman-Furnas K, Rossi AH, Wilkinson EG, Strader LC, Casal JJ.   +6 more
europepmc   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Erratum to “Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients”

Stem Cells International, 2020
Tadashi Takaki, Azusa Inagaki, Kazuhisa Chonabayashi, Keiji Inoue, Kenji Miki, Seiko Ohno, Takeru Makiyama, Minoru Horie, Yoshinori Yoshida   +8 more
doaj   +1 more source