Results 171 to 180 of about 5,651,556 (349)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Identification and Characterization of a Minimal Apoptotic Domain from p53

The Scientific World Journal, 2001
Kevin M. Ryan, Karen H. Vousden
doaj   +1 more source

Artesunate inhibits the growth and induces apoptosis of human gastric cancer cells by downregulating COX-2

, 2015
Ping Zhang, Hesheng Luo, Ming Li, Shiyun Tan   +3 more
openalex   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells. [PDF]

Pharmacol Res Perspect
Li X, Liao XQ, Chen WR, Wu T, Li JX, Wang L, He BS, Qin X, Luo JQ.   +8 more
europepmc   +1 more source

The Effect of Novel Fluorapatite Surfaces on Osteoblast-Like Cell Adhesion, Growth, and Mineralization

, 2010
Jun Liu, Taocong Jin, Syweren Chang, Agata Czajka-Jakubowska, Zhaocheng Zhang, Jacques E. Nör, Brian H. Clarkson   +6 more
openalex   +2 more sources

Isoflavones regulate secretion of leukemia inhibitory factor and transforming growth factor β and expression of glycodelin in human endometrial epithelial cells [PDF]

, 2007
Jin‐Wen Xu, Naomi Yasui, Katsumi Ikeda, Weijun Pan, June Watanabe, Masahide Shiotani, Atsushi Yanaihara, Tomohiro Miki, Yukio Yamori   +8 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth. [PDF]

Oncol Rep
Tu K, Li C, Zheng X, Yang W, Yao Y, Liu Q.   +5 more
europepmc   +1 more source