Stem Cell Reports, 2015 Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of the neuromuscular junction (NMJ) precede the motor neuronal loss.
Michiko Yoshida +13 more
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An Interaction between Insulin-like Growth Factor-binding Protein 2 (IGFBP2) and Integrin α5 Is Essential for IGFBP2-induced Cell Mobility [PDF]
, 2006 George K. Wang +3 more
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Journal of Integrative Agriculture, 2013 DNA barcodes have been proposed as a shortcut to provide species identification and as a way to accelerate the discovery of new species. A number of candidate gene regions have been suggested as possible barcodes for animals and plants, but for the ...
Li HUANG +5 more
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Cell facilitation promotes growth and survival under drug pressure in breast cancer [PDF]
, 2023 Rena Emond +9 more
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Development of chimeric antigen receptor T cells targeting cancer-expressing podocalyxin
Regenerative TherapyChimeric Antigen Receptor (CAR)-T cell therapy has revolutionized the treatment of CD19-positive B-cell malignancies. However, the field is rapidly evolving to target other antigens, such as podocalyxin (PODXL), a transmembrane protein implicated in ...
Yuta Mishima +7 more
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Truncation of Annexin A1 Is a Regulatory Lever for Linking Epidermal Growth Factor Signaling with Cytosolic Phospholipase A2 in Normal and Malignant Squamous Epithelial Cells [PDF]
, 2007 Masakiyo Sakaguchi +7 more
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CSMA: A Standalone and ImageJ-Compatible Tool for Enhanced Wound Healing Assay Analysis
IEEE AccessAccurate quantification of wound closure in cell migration assays is crucial yet challenging. Still, existing methods often underperform due to omitting cell detection within the wound area, resulting in biased outcomes.
Tri Thanh Pham +4 more
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A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability [PDF]
, 2023 Zhichun Zhang +4 more
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Nature CommunicationsAnti-pituitary-specific transcription factor (PIT)−1 hypophysitis is an autoimmune disease characterized by hormone secretion impairment from PIT-1-expressing pituitary cells, accompanied by malignancies with ectopic PIT-1 expression.
Keitaro Kanie +12 more
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Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors. [PDF]
, 1996 Ariane Mallat +12 more
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