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Regulatory Role of Cell Division Rules on Tissue Growth Heterogeneity
The coordination of cell division and cell expansion are critical to normal development of tissues. In plants, cell wall mechanics and the there from arising cell shapes and mechanical stresses can regulate cell division and cell expansion and thereby ...
Karen Alim +2 more
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Spatiotemporal coordination of cell division and growth during organ morphogenesis.
A developing plant organ exhibits complex spatiotemporal patterns of growth, cell division, cell size, cell shape, and organ shape. Explaining these patterns presents a challenge because of their dynamics and cross-correlations, which can make it ...
Samantha Fox +12 more
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A modeling study on how cell division affects properties of epithelial tissues under isotropic growth. [PDF]
Cell proliferation affects both cellular geometry and topology in a growing tissue, and hence rules for cell division are key to understanding multicellular development.
Patrik Sahlin, Henrik Jönsson
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Control of cell growth, division and death: information processing in living cells. [PDF]
Tyson JJ, Novak B.
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Quo vadis cell growth and division?
Philipp Kaldis
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T-cell immunotherapies, such as CAR-T immunotherapy, are being developed against a wide variety of diseases. Here the authors report the feeder-free, scalable differentiation of human induced pluripotent cells (iPSCs) to T-cells with T-cell receptor ...
Shoichi Iriguchi +19 more
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Cytokinesis-based constraints on polarized cell growth in fission yeast. [PDF]
The rod-shaped fission yeast Schizosaccharomyces pombe, which undergoes cycles of monopolar-to-bipolar tip growth, is an attractive organism for studying cell-cycle regulation of polarity establishment.
K Adam Bohnert, Kathleen L Gould
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Despite the universality of metabolic pathways, malignant cells were found to have their metabolism reprogrammed to generate energy by glycolysis even under normal oxygen concentrations (the Warburg effect).
Halina Witkiewicz +2 more
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Most cancer patients die of metastatic disease, not primary tumors, while biological mechanisms leading to metastases remain unclear and effective therapies are missing.
Halina Witkiewicz +2 more
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Net growth of microbial populations, that is, changes in abundances over time, can be studied using 16S rRNA fluorescence in situ hybridization (FISH). However, this approach does not differentiate between mortality and cell division rates.
Jan D. Brüwer +8 more
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