Results 11 to 20 of about 11,093,569 (425)
Hypoxia, Metabolism and Immune Cell Function [PDF]
Biomedicines, 2018 Hypoxia is a hallmark of inflamed, infected or damaged tissue, and the adaptation to inadequate tissue oxygenation is regulated by hypoxia-inducible factors (HIFs).
Ewelina Krzywińska, C. Stockmann
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Hypoxia Onset in Mesenchymal Stem Cell Spheroids: Monitoring With Hypoxia Reporter Cells [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The therapeutic and differentiation potential of human mesenchymal stems cells (hMSCs) makes these cells a promising candidate for cellular therapies and tissue engineering. On the path of a successful medical application of hMSC, the cultivation of cells in a three-dimensional (3D) environment was a landmark for the transition from simple two ...
Carola Schmitz +5 more
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Hypoxia in Cell Reprogramming and the Epigenetic Regulations [PDF]
Frontiers in Cell and Developmental Biology, 2021 Cellular reprogramming is a fundamental topic in the research of stem cells and molecular biology. It is widely investigated and its understanding is crucial for learning about different aspects of development such as cell proliferation, determination of cell fate and stem cell renewal.
Yong Li +3 more
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Tumor Hypoxia and Circulating Tumor Cells [PDF]
International Journal of Molecular Sciences, 2020 Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
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Role of Hypoxia in the Control of the Cell Cycle [PDF]
International Journal of Molecular Sciences, 2021 The cell cycle is an important cellular process whereby the cell attempts to replicate its genome in an error-free manner. As such, mechanisms must exist for the cell cycle to respond to stress signals such as those elicited by hypoxia or reduced oxygen availability. This review focuses on the role of transcriptional and post-transcriptional mechanisms
Jimena Druker +5 more
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Ferroptosis Regulated by Hypoxia in Cells
Cells, 2023 Ferroptosis is an oxidative damage-related, iron-dependent regulated cell death with intracellular lipid peroxide accumulation, which is associated with many physiological and pathological processes. It exhibits unique features that are morphologically, biochemically, and immunologically distinct from other regulated cell death forms.
Xiangnan Zheng, Yuqiong Liang, Cen Zhang
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The Feyrter cell in hypoxia [PDF]
Thorax, 1973 Moosavi, H., Smith, P., and Heath, D. (1973).Thorax,28, 729-741. The Feyrter cell in hypoxia. It is clear that the bronchial tree has functions beyond the mere conduction of air into the alveolar spaces. In addition to the familiar ciliated respiratory epithelial cells the bronchus is lined by non-ciliated Clara and Feyrter cells.
Donald Heath +2 more
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Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function [PDF]
Arthritis Research & Therapy, 2009 With little in the way of effective therapeutic strategies to target the innate immune response, a better understanding of the critical pathways regulating neutrophil and macrophage responses in inflammation is key to the development of novel therapies.
Walmsley, SR, Chilvers, ER, Whyte, MKB
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Hypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell types. [PDF]
PLoS ONE, 2012 Hypoxia plays an important role in the resistance of tumour cells to chemotherapy. However, the exact mechanisms underlying this process are not well understood. Moreover, according to the cell lines, hypoxia differently influences cell death.
Audrey Sermeus +8 more
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A simple mathematical model of cyclic hypoxia and its impact on hypofractionated radiotherapy [PDF]
Medical Physics, 50, 1893-1904 (2023), 2022 There is evidence that the population of cells that experience fluctuating oxygen levels are more radioresistant than chronically hypoxic ones and hence, this population may determine radiotherapy (RT) response, in particular for hypofractionated RT, where reoxygenation may not be as prominent.
arxiv +1 more source