Results 211 to 220 of about 349,615 (316)

Room 224-226, 10/16/2000 3: 30 PM - 5: 00 PM (PD) Hypoxia Increases ICAM-1-Mediated Adherence of Neutrophils to Alveolar Epithelial Cells [PDF]

, 2000
Caveh Madjdpour, Thomas Pasch, Beatrice Beck‐Schimmer   +2 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Salmonella Typhi gut invasion drives hypoxic immune subsets associated with disease outcomes. [PDF]

Nat Commun
Bossel Ben-Moshe N, Hen-Avivi S, Levy Efrati L, Veinman L, Hill J, O'Connor D, Verheul M, Stockdale L, McLean F, Pollard AJ, Avraham R.   +10 more
europepmc   +1 more source

Nonhypoxic Pathway Mediates the Induction of Hypoxia-inducible Factor 1α in Vascular Smooth Muscle Cells

, 2000
Darren E. Richard, Edurne Berra, Jacques Pouysségur   +2 more
openalex   +1 more source

Genetic Engineering Methods in Primary T Cells

Advanced Therapeutics, EarlyView.
Primary T cells can be engineered to confer them with novel therapeutic functions, allowing them to treat a variety of conditions. Genetic engineering can be either stable or transient, aiming to either express or inhibit a target gene. This review discusses the various genetic engineering tools available as well as their characteristics and ...
Anthony Youssef, Hui‐Shan Li
wiley   +1 more source

Transcriptomic Alterations of Canine Histiocytic Sarcoma Cells in Response to Different Stressors. [PDF]

Int J Mol Sci
Asawapattanakul T, Schughart K, von Köckritz-Blickwede M, Armando F, Claus P, Baumgärtner W, Puff C.   +6 more
europepmc   +1 more source

Extracellular Matrix Composition and Hypoxia Regulate the Expression of HLA-G and Integrins in a Human Trophoblast Cell Line1

, 2000
Brian A. Kilburn, Jun Wang, Zophia M. Duniec-Dmuchkowski, Richard E. Leach, Roberto Romero, D. Randall Armant   +5 more
openalex   +1 more source

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Crosstalk between the aryl hydrocarbon receptor and hypoxia-inducible factor 1α pathways in human islet models. [PDF]

Islets
Gang N, van Allen KA, Willmore WG, Lynn FC, Bruin JE.   +4 more
europepmc   +1 more source