Results 221 to 230 of about 375,784 (265)

Sphingosine kinase 1 is dysregulated via hypoxia-inducible factor 1α in oral squamous cell carcinoma. [PDF]

Indian J Med Res
Pandey R, Vishwakarma S, Gupta V, Arya N, Das S, Chowdhary R, Kumar A.   +6 more
europepmc   +1 more source

CoCl₂-induced alterations in antioxidative and inflammatory marker expression in an siRNA-based in vitro model of aniridia-associated limbal epithelial dysfunction. [PDF]

BMC Ophthalmol
Hsu SL, Szentmáry N, Fries FN, Li Z, Chai N, Seitz B, Amini M, Suiwal S, Stachon T.   +8 more
europepmc   +1 more source

GRB2 Promotes Sorafenib Resistance in Hepatocellular Carcinoma Cells Under Hypoxia by Activating the PI3K/AKT Signaling Pathway. [PDF]

J Hepatocell Carcinoma
He J, Kong Y, Wang Y, Fang Q, Wu H, Du K, Luo Y, Tan J, Yin H, Lin H, Li M.   +10 more
europepmc   +1 more source

Current Studies on the Hypoxic Tumor Microenvironment in Thyroid Cancer: From Molecular Mechanisms to Clinical Therapeutic Perspectives. [PDF]

Biomedicines
Peng X, Ma L, Chang W.
europepmc   +1 more source

Growth of Oxygen Environment of the Newborn Vocal Fold Maculae Flavae as a Stem Cell Niche. [PDF]

Laryngoscope Investig Otolaryngol
Sato K, Chitose SI, Sato F, Sato K, Ono T, Umeno H.   +5 more
europepmc   +1 more source

Role of Hypoxia in the Control of the Cell Cycle [PDF]

International Journal of Molecular Sciences, 2021
The cell cycle is an important cellular process whereby the cell attempts to replicate its genome in an error-free manner. As such, mechanisms must exist for the cell cycle to respond to stress signals such as those elicited by hypoxia or reduced oxygen availability. This review focuses on the role of transcriptional and post-transcriptional mechanisms
S Rocha, Dilem Shakir, James Wilson
exaly   +4 more sources

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Intermittent hypoxia: cell to system

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2001
This symposium was organized to present research dealing with the effects of intermittent hypoxia on cardiorespiratory systems and cellular mechanisms. The pattern of neural impulse activity has been shown to be critical in the induction of genes in neuronal cells and involves distinct signaling pathways.
N R, Prabhakar, R D, Fields, T, Baker, E C, Fletcher   +3 more
openaire   +2 more sources

In vitro intermittent hypoxia: challenges for creating hypoxia in cell culture

Respiratory Physiology & Neurobiology, 2003
Intermittent hypoxia has been implicated in morbidities associated with sleep apnea, and may be a novel cellular signal for inflammation [J. Appl. Physiol. 90 (2001) 1986]. Standard cell culture has two major limitations for studying the effects of steady-state P(O(2)) and intermittent hypoxia.
James E, Baumgardner, Cynthia M, Otto
openaire   +2 more sources

Stem Cells, Hypoxia and Hypoxia-Inducible Factors

2009
Oxygen is a critical environmental factor that regulates the fate of stem cells. In this review, our aims are twofold: (i) to consider the contribution of oxygen tension to the environmental niches in which stem cells and their progeny find themselves and which have a role in determining their fate, and (ii) to define the regulatory networks that ...
Suzanne M. Watt, Grigorios Tsaknakis, Sinead P. Forde, Lee Carpenter   +3 more
openaire   +1 more source