Results 231 to 240 of about 619,300 (360)

The hypoxia signature across skeletal progenitor cells [PDF]

Elena Sabini, Ernestina Schipani
openalex   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source

A Response to Article “Rho-Associated Protein Kinase Inhibitor and Hypoxia Synergistically Enhance the Self-Renewal, Survival Rate, and Proliferation of Human Stem Cells” [Letter]

, 2022
Frans Dany, Ratih Rinendyaputri
openalex   +2 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Roles of the Altitude-Adapted Immune Microenvironment in Pulmonary Vascular Remodeling in High-Altitude Pulmonary Hypertension: A Review. [PDF]

Med Sci Monit
Li Y, Xing H, Liu Y, Li F, Yang D, Miao Q, Li H, Li X, Yang S, Fu Y.   +9 more
europepmc   +1 more source

The Vav3 oncogene enhances the malignant potential of prostate cancer cells under chronic hypoxia

, 2013
健一 平井
openalex   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Targeting ceramide metabolism to restore hypoxia-induced apoptosis in p53-deficient colon cancer cells. [PDF]

PLoS One
Mechleb K, Hourani N, Fakhry M, Alyamani OA, Hage-Sleiman R, Younes H, Fayad AA, Soudani N, Sakr A, Darwiche N, Nemer G, Saab R, Mrad M, Dbaibo G.   +13 more
europepmc   +1 more source

Resveratrol Reduces the Hypoxia-Induced Resistance to Doxorubicin in Breast Cancer Cells

, 2014
Takakazu Mitani, Yuta Ito, Naoki Harada, Yoshihisa Nakano, Hiroshi Inui, Hitoshi Ashida, Ryoichi Yamaji   +6 more
openalex   +2 more sources

67 UTILIZATION OF OLEATE AND D-BETA-OH-BUTYRATE (BOHB) AS ALTERNATE ENERGY FUELS IN BRAIN CELL CULTURES OF NEWBORN MICE AFTER HYPOXIA AT DIFFERENT GLUCOSE CONCENTRATIONS [PDF]

, 1988
E Bossi, Norbert Herschkcwltz, Eva Kohler   +2 more
openalex   +1 more source