Results 11 to 20 of about 2,773,088 (322)
Characteristics of Whale Müller Glia in Primary and Immortalized Cultures
Frontiers in Neuroscience, 2022 Müller cells are the principal glial cells in the retina and they assume many of the functions carried out by astrocytes, oligodendrocytes and ependymal cells in other regions of the central nervous system.
Xandra Pereiro +8 more
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Fibroblasts cell lines misclassified as cancer cell lines [PDF]
, 2017 Large collections of immortalized cancer cell lines have been widely used as model systems for cancer research and drug discovery. Some of these models however display more fibroblast-like than cancer-like characteristics based on their genetic and genomic characterization. The correct annotation of these cell lines remains a challenge. Here, we report
de Weck, Antoine +2 more
openaire +2 more sources
, 2015 The human colon adenocarcinoma cell line HT29, is not only used to study the biology of human colon cancers, but it is receiving special interest in studies focused on food digestion and bioavailability due to the ability to express characteristics of mature intestinal cells. In the differentiated phenotype, they are able to form a monolayer with tight
Martínez-Maqueda, D. +2 more
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Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants
Frontiers in Genome Editing, 2022 CRISPR/Cas9, base editors and prime editors comprise the contemporary genome editing toolbox. Many studies have optimized the use of CRISPR/Cas9, as the original CRISPR genome editing system, in substituting single nucleotides by homology directed repair
Inga Usher +8 more
doaj +1 more source
Gynaecological cancers and their cell lines [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractCell lines are widely used for various research purposes including cancer and drug research. Recently, there have been studies that pointed to discrepancies in the literature and usage of cell lines. That is why we have prepared a comprehensive overview of the most common gynaecological cancer cell lines, their literature, a list of currently ...
Kristijan Skok +7 more
openaire +3 more sources
Study of dose-dependent combination immunotherapy using engineered T cells and IL-2 in cervical cancer [PDF]
, 2020 Adoptive T cell based immunotherapy is gaining significant traction in cancer treatment. Despite its limited success, so far, in treating solid cancers, it is increasingly successful, demonstrating to have a broader therapeutic potential. In this paper we develop a mathematical model to study the efficacy of engineered T cell receptor (TCR) T cell ...
arxiv +1 more source
Differential Cell Line Susceptibility to Crimean-Congo Hemorrhagic Fever Virus
Frontiers in Cellular and Infection Microbiology, 2021 Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne viral disease of global concerns due to the increasing incidence and lack of effective treatments.
Shiyu Dai +8 more
doaj +1 more source
A Comparative Study Of HOTAIR Expression In Breast Cancer Patient Tissues And Cell Lines [PDF]
Cell Journal, 2020 Objective Recent data suggest that increased levels of the HOTAIR long non-coding RNA (lncRNA) are involved in the development of various types of malignancy, including breast cancer.
Asghar Arshi +7 more
doaj +1 more source
One dimensional cell motility patterns [PDF]
Phys. Rev. Research 2, 033237 (2020), 2020 During migration cells exhibit a rich variety of seemingly random migration patterns, which makes unraveling the underlying mechanisms that control cell migration a daunting challenge. For efficient migration cells require a mechanism for polarization, so that traction forces are produced in the direction of motion, while adhesion is released to allow ...
arxiv +1 more source
Frontiers in Cell and Developmental Biology, 2021 Matrix metalloproteinases (MMPs) are zinc- and calcium- dependent endopeptidases that play pivotal roles in many biological processes. The expression of several MMPs in the central nervous system (CNS) have been shown to change in response to injury and ...
Scoty Hearst +11 more
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