Results 31 to 40 of about 2,773,088 (322)
Normal epithelial and triple-negative breast cancer cells show the same invasion potential in rigid spatial confinement [PDF]
The extra-cellular microenvironment has a fundamental role in tumor growth and progression, strongly affecting the migration strategies adopted by single cancer cells during metastatic invasion. In this study, we use a novel microfluidic device to investigate the ability of mesenchymal and epithelial breast tumor cells to fluidize and migrate through ...
arxiv +1 more source
Background: The tyrosinase enzyme catalysis monophenols to melanin pigments through the melanogenesis process. For this reason, various inhibitors have been studied for enzyme regulations in melanogenesis abnormalities in both the food and cosmetics ...
Negar Taherkhani1+3 more
doaj +1 more source
Random line tessellations of the plane: statistical properties of many-sided cells [PDF]
We consider a family of random line tessellations of the Euclidean plane introduced in a much more formal context by Hug and Schneider [Geom. Funct. Anal. 17, 156 (2007)] and described by a parameter \alpha\geq 1. For \alpha=1 the zero-cell (that is, the cell containing the origin) coincides with the Crofton cell of a Poisson line tessellation, and for
arxiv +1 more source
The most sensitive cell culture system for the isolation of foot-and-mouth disease virus (FMDV) is primary bovine thyroid (BTY) cells. However, BTY cells are seldom used because of the challenges associated with sourcing thyroids from FMDV-negative ...
Ashley R. Gray+5 more
doaj +1 more source
Cell line for (Design, Molecular Docking, Synthesis and Preliminary Evaluation of Hybrid Molecules of Benzothiazole Linked with Hydroxamate by Disulfide Bond and Certain Linkers as HDACs Inhibitors)
openaire +2 more sources
Pattern Formation of Glioma Cells: Effects of Adhesion [PDF]
We investigate clustering of malignant glioma cells. \emph{In vitro} experiments in collagen gels identified a cell line that formed clusters in a region of low cell density, whereas a very similar cell line (which lacks an important mutation) did not cluster significantly. We hypothesize that the mutation affects the strength of cell-cell adhesion. We
arxiv +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Development and cytotoxic response of two proliferative MDA- MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines [PDF]
Triple-Negative Basal-Like tumors, representing 15 to 20% of breast cancers, are very aggressive and with poor prognosis. Targeted therapies have been developed extensively in preclinical and clinical studies to open the way for new treatment strategies.
arxiv +1 more source
Crawling and turning in a minimal reaction-diffusion cell motility model: coupling cell shape and biochemistry [PDF]
We study a minimal model of a crawling eukaryotic cell with a chemical polarity controlled by a reaction-diffusion mechanism describing Rho GTPase dynamics. The size, shape, and speed of the cell emerge from the combination of the chemical polarity, which controls the locations where actin polymerization occurs, and the physical properties of the cell,
arxiv +1 more source
Background In B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL), chromosomal translocations are strongly associated with prognoses. RNA sequencing (RNA‐seq) is a powerful technology that reveals a close correlation between types of translocation ...
Minori Tamai+10 more
doaj +1 more source