Results 41 to 50 of about 5,658,856 (358)

Using microelectrode models for real time cell-culture monitoring [PDF]

, 2011
This paper proposes a cell-microelectrode model for cell biometry applications, based on the area overlap as main parameter. The model can be applied to cell size identification, cell count, and their extension to cell growth and dosimetry protocols ...
Cañete, Daniel, Daza Navarro, María Paula, Yúfera García, Alberto   +2 more
core   +1 more source

Do-it-yourself instrument integration into an existing mammalian cell line development automation platform

SLAS Technology
Laboratory automation in the biopharmaceutical industry as a rule requires contracted service from highly professional automation solution provider, at times involving the purchase and development of specialized or customized hardware and software, which
Jie Ding, Kee Wee Tan, Xiaoyue Chen
doaj   +1 more source

Generation and characterization of a mitotane-resistant adrenocortical cell line [PDF]

, 2020
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy.
Bachmann, Sebastian, Bahethi, Rohini, Beule, Dieter, Choi, Murim, Eisenhofer, Graeme, Liebisch, Gerhard, Messerschmidt, Clemens, Obermayer, Benedikt, Peitzsch, Mirko, Scholl, Ute I., Schrade, Petra, Seidel, Eric, Walenda, Gudrun, Wallace, Paal, Yoo, Taekyeong   +14 more
core   +2 more sources

Colchicine modulates TIMP1, MMP1, and pMAP4 expression to enhance extracellular matrix degradation in 3T3 fibroblast-mediated myocardial infarction [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Cardiovascular disease is a leading cause of mortality worldwide. Following acute myocardial infarction (AMI), cardiac cells release many cytokines and proteolytic enzymes that regulate the extracellular matrix (ECM), including matrix ...
Saskia Dyah Handari, Mohammad Saifur Rahman, Djanggan Sargowo, Aulanni’am Aulanni’am, Bayu Lestari, Delvac Oceandy   +5 more
doaj   +1 more source

An Empirical-Mathematical Approach for Calibration and Fitting Cell-Electrode Electrical Models in Bioimpedance Tests [PDF]

, 2018
This paper proposes a new yet efficient method allowing a significant improvement in the on-line analysis of biological cell growing and evolution.
Daza Navarro, María Paula, Huertas Sánchez, Gloria, Maldonado-Jacobi, Andrés, Martín Rubio, María Esther, Olmo Fernández, Alberto, Pérez García, Pablo, Rueda Rueda, Adoración (Coordinador), Serrano Viseas, Juan Alfonso, Sánchez Aguayo, Inmaculada (Coordinador), Yúfera García, Alberto   +9 more
core  

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Utility of a Large Series of B‐Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model System

Cancer Medicine
Background In B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL), chromosomal translocations are strongly associated with prognoses. RNA sequencing (RNA‐seq) is a powerful technology that reveals a close correlation between types of translocation ...
Minori Tamai, Chiaki Komatsu, Keiko Kagami, Shin Kasai, Koshi Akahane, Kumiko Goi, Kanji Sugita, Chihiro Tomoyasu, Toshihiko Imamura, Hiroaki Goto, Takeshi Inukai   +10 more
doaj   +1 more source

The Emerging Role of miRNAs in HTLV-1 Infection and ATLL Pathogenesis

Viruses, 2015
Human T-cell leukemia virus (HTLV)-1 is a human retrovirus and the etiological agent of adult T-cell leukemia/lymphoma (ATLL), a fatal malignancy of CD4/CD25+ T lymphocytes.
Ramona Moles, Christophe Nicot
doaj   +1 more source

Cell patterning on photolithographically defined parylene-C:SiO2 substrates [PDF]

, 2014
Cell patterning platforms support broad research goals, such as construction of predefined in vitro neuronal networks and the exploration of certain central aspects of cellular physiology.
Brennan, Paul M, Bunting, Andrew S, Hughes, Mark A, Murray, Alan F, Shipston, Mike J   +4 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source