Results 61 to 70 of about 5,448,677 (358)

Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells [PDF]

open access: yes, 1999
We provide evidence from a newly established, conditionally immortal cell line (UB/UE-1) that vestibular supporting cells from the mammalian inner ear can differentiate postnatally into more than one variant of hair cell.
Holley, M.C.   +4 more
core   +1 more source

A Role of the Choroid Plexus in Transplantation Therapy

open access: yesCell Transplantation, 2005
The choroid plexuses (CPs) play pivotal roles in the most basic aspects of neural function. Some of the roles of the CP include maintaining the extracellular milieu of the brain by actively modulating chemical exchange between the CSF and brain ...
Dwaine F. Emerich   +3 more
doaj   +1 more source

Cell Line Derived Xenograft Mouse Models Are a Suitable in vivo Model for Studying Tumor Budding in Colorectal Cancer

open access: yesFrontiers in Medicine, 2019
Tumor budding (TB) is an important prognostic parameter in colorectal cancer (CRC) and associated with metastasis. However, the mechanisms of TB have not been fully elucidated and a major limitation is the absence of in vivo models.
Laurent M. C. Georges   +6 more
doaj   +1 more source

Establishment and Characterization of Feline Mammary Tumor Patient-Derived Xenograft Model

open access: yesAnimals, 2021
Feline mammary tumor is a relatively commonly diagnosed neoplasm in the cat. Development of new veterinary cancer therapies is limited by the shortage of in vivo models that reproduce tumor microenvironment and metastatic progression. Four feline mammary
Hsiao-Li Chuang   +9 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Glial Cell Lines: An Overview [PDF]

open access: yesNeurochemical Research, 2010
The importance and essential functions of glial cells in the nervous system are now beginning to be understood and appreciated. Glial cell lines have been instrumental in the elucidation of many of these properties. In this Overview, the origin and properties of most of the existing cell lines for the major glial types: oligodendroglia, astroglia ...
George H. De Vries, Anne I. Boullerne
openaire   +3 more sources

The Comparative Invasiveness of Endometriotic Cell Lines to Breast and Endometrial Cancer Cell Lines

open access: yesBiomolecules, 2023
Endometriosis is an invasive condition that affects 10% of women (and people assigned as female at birth) worldwide. The purpose of this study was to characterize the relative invasiveness of three available endometriotic cell lines (EEC12Z, iEc-ESCs, tHESCs) to cancer cell lines (MDA-MB-231, SW1353 and EM-E6/E7/TERT) and assess whether the relative ...
Katherine Ellis, Rachael Wood
openaire   +4 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Cell Line Monolayer Tissue Culture FKDL dan Cell Line OL sebagai Media Penumbuh Virus pada Pengembangan Bioteknologi Biomolekuler (Penelitian Eksperimental Laboratoris) [PDF]

open access: yes, 2012
Cell line sangatlah penting dalam dunia medis, khususnya dibidang diagnosis, produksi vaksin maupun dibidang bioteknologi serta biomolekuler. Berbagai penelitian telah dilakukan untuk tehnik pembuatan Cell Line Monolayer Tissue Culture.
Hasdianah, H. (Hasdianah)
core  

Establishment and characterization of mouse metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma organoids

open access: yesScientific Reports
Metabolic dysfunction-associated steatohepatitis (MASH) is a form of chronic liver inflammation associated with metabolic syndrome, such as obesity and a major cause of hepatocellular carcinoma (HCC).
Sumin Kim   +6 more
doaj   +1 more source

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