Results 91 to 100 of about 9,017,426 (338)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Enhancement of Gene Silencing Effect and Membrane Permeability by Peptide-Conjugated 27-Nucleotide Small Interfering RNA

Molecules, 2012
Two different sizes of siRNAs, of which one type was 21-nucleotide (nt) siRNA containing 2-nt dangling ends and the other type was 27-nt siRNA with blunt ends, were conjugated with a nuclear export signal peptide of HIV-1 Rev at the 5′-sense end ...
Toshio Seyama, Yasuhiro Morita, Yuichiro Sato, Kazuyoshi Yanagihara, Takanori Kubo   +4 more
doaj   +1 more source

Study on membrane characteristics of alginate-chitosan microcapsule with cell growth

, 2011
Alginate-chitosan (AC) microcapsule with polyelectrolyte complex (PEC) membrane has been attractive in biotechnological area such as cell immobilization fermentation.
Zheng, Guoshuang, Guoshuang Zheng, Yu, Weiting, Liu, Xiudong, Ying Zhang, Zhang, Ying, Song, Huiyi, Huiyi Song, Xiaojun Ma, Xiudong Liu, Ma, Xiaojun, Weiting Yu   +11 more
core   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Current Density Performances in Poly Ether Ether Keton Membrane for Direct Methanol Fuel Cells [PDF]

, 2012
The objective of this study focuses on the characterization of poly ether ether ketone (PEEK) membranes for direct methanol fuel cells (DMFC) application. The PEEK membrane was modified with sulfonation in NMP solvent.
E. L. , Dewi, A. , Dhuhita, T. D. , Kusworo, M.N.A. , Mohd Norddin, D. K. , Arti, A.F. , Ismail   +5 more
core   +1 more source

Cyclic peptide membrane permeability prediction using deep learning model based on molecular attention transformer

Frontiers in Bioinformatics
Membrane permeability is a critical bottleneck in the development of cyclic peptide drugs. Experimental membrane permeability testing is costly, and precise in silico prediction tools are scarce.
Dawei Jiang, Zixi Chen, Zixi Chen, Hongli Du   +3 more
doaj   +1 more source

The cell membrane permeability coefficients of Sf21 for 1.5 M glycerol.

, 2013
The cell membrane permeability coefficients of Sf21 for 1.5 M glycerol.
Gang Zhao (161405), Cui Yue (453858), Jianye Wang (453856), Dayong Gao (453859), Kaixuan Zhu (453857), Jian Ren (175424)   +5 more
core   +1 more source

Ultrasound microbubble induced endothelial cell permeability [PDF]

, 2006
Ultrasound microbubbles have the ability to enhance cell permeability that can be used to deliver drugs intervascular through the transfer of extracellular molecules into cells.
Versluis, Michel; id_orcid, Emmer, M., ten Cate, F.J., van Wamel, A., Kooiman, K., de Jong, N., M. Emmer, A. van Wamel, M. Versluis, F.J. ten Cate, N. de Jong, K. Kooiman   +11 more
core   +1 more source