Results 81 to 90 of about 9,017,426 (338)

Basic examination of the cell membrane permeability of site probe agents using a cell membrane plate [PDF]

P(論文)Drug efficacy depends on the amount of a preparation reaching the target tissue (grade of tissue transfer). In this experiment, we established the normal albumin concentration of a healthy adult (600 μ M) or a low-albumin state indicating marked ...
7000, 7002, KAWAI, Keiichi, オガタ, ケンジ, ニシオ, トヨタカ, 1021, 9000006346074, 1020, 7161, 徳永, 仁, 1338, 1019, 9000006682222, 1014, 1013, 1012, カワイ, ケイイチ, Tokunaga, Jin, 緒方, 賢次, 高村, 徳人, 西尾, 豊隆, ヨシダ, ヒロキ, 1348, 1000020369169, 1347, 1028, YOSHIDA, Hiroki, 1027, 1026, KONDO, Teruyoshi, 7008, 9000004722867, 川井, 恵一, 7007, NAGATA, Masashi, 20369169, 1000030204663, 近藤, 照義, 9000002747927, 吉田, 裕樹, 90469411, 60369171, Takamura, Norito, 9000002747765, Ogata, Kenji, 1357, 9000002747919, 1758, 9000006242775, 7156, 7155, 1000060369171, トクナガ, ジン, ナガタ, マサシ, 永田, 将司, 1000090509580, NISHIO, Toyotaka, 1766, タカムラ, ノリト, 1762, コンドウ, テルヨシ, 90509580, 1000090469411, 5925   +63 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Integrin-mediated membrane blebbing is dependent on the NHE1 and NCX1 activities. [PDF]

, 2011
Integrin-mediated signal transduction and membrane blebbing have been well studied to modulate cell adhesion, spreading and migration^1-6^. However, the relationship between membrane blebbing and integrin signaling has not been explored.
Wei-Lien Tseng, Yu-Sun Chang, Tsung-Yu Chen, Tien-Shen Lew, Szecheng J. Lo, Yung-Hsiang Yi, Chi-Hung Lin, Ching-Ping Tseng, Chih-Yung Tang   +8 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Sarcophine-Diol Inhibits Expression of COX-2, Inhibits Activity of cPLA2, Enhances Degradation of PLA2 and PLCγ1 and Inhibits Cell Membrane Permeability in Mouse Melanoma B16F10 Cells

Marine Drugs, 2012
Sarcophine-diol (SD) is a semi-synthetic derivative of sarcophine with a significant chemopreventive effect against non-melanoma skin cancer both in vitro and in vivo.
Sherief Khalifa, Hesham Fahmy, Safwat A. Ahmed, Pratik Muley, Pawel T. Szymanski   +4 more
doaj   +1 more source

Lens Cell Membrane Permeability and Cataract Formation.

Experimental Biology and Medicine, 1964
SummaryAnalyses of rat lenses just before and just after the appearance of diabetic or galactose cataracts demonstrate that this event is accompanied by an abrupt disruption of the cell membranes of the lens. The concentrations of polyol, glucose and fructose in the lens approach those in the blood; and the extracellular space as determined with ...
J W, PATTERSON, K W, BUNTING
openaire   +2 more sources

A model for methanol transport through Nafion (R) membrane in diffusion cell

, 2008
The transport of methanol through Nafion (R) membrane in diffusion cell is investigated using the open circuit potential method at different initial methanol concentration solutions.
Wang, Suli, Sun, Gongquan, Wu, Zhimou, Jin, Wei, Hou, Hongying, Wei Jin, Hongying Hou, Suli Wang, Gongquan Sun, Zhimou Wu   +9 more
core   +1 more source

Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin [PDF]

, 2002
Schaschke N, Deluca D, Assfalg-Machleidt I, Hohneke C, Sommerhoff CP, Machleidt W. Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin.
Schaschke, Norbert, Assfalg-Machleidt, Irmgard, Deluca, D, Sommerhoff, CP, Assfalg-Machleidt, I, Machleidt, Werner, Deluca, Dominga, Sommerhoff, Christian P., Hohneke, C, Höhneke, Clara, Machleidt, W   +10 more
core   +1 more source

Amide-to-Ester Substitution Improves Membrane Permeability of a Cyclic Peptide Without Altering Its Three-Dimensional Structure [PDF]

, 2020
Cyclic peptides are attractive molecules as inhibitors with high affinity and selectivity against intracellular protein-protein interactions (PPIs).
Chad, Townsend, R. Scott, Lokey, Yuki, Hosono, Hsiau-Wei, Lee, Jumpei, Morimoto, Colin N., Kelly, Shinsuke, Sando, Matthew R., Naylor   +7 more
core   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source