Results 61 to 70 of about 6,170,961 (296)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Preparative scale production of functional mouse aquaporin 4 using different cell-free expression modes [PDF]

, 2010
The continuous progress in the structural and functional characterization of aquaporins increasingly attracts attention to study their roles in certain mammalian diseases.
Volker Dötsch, Lian, Jiazhang, Kaldenhoff Ralf, Dötsch, Volker, Frank Bernhard, Xiangcheng Zhu, Cen, Peilin, Dötsch Volker, Lei Kai, Zhinan Xu, Xu, Zhinan, Peilin Cen, Kai Lei, Kai, Lei, Cen Peilin, Kaldenhoff, Ralf, Xu Zhinan, Zhu Xiangcheng, Ralf Kaldenhoff, Lian Jiazhang, Jiazhang Lian, Bernhard, Frank, Zhu, Xiangcheng, Bernhard Frank   +23 more
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Denitrification using immersed membrane bioreactors

, 2008
Nitrate is practically ubiquitous in waters abstracted for municipal potable water production in Europe due to decades of intensive agricultural practice.
McAdam, Ewan J.
core   +7 more sources

IDEAL-Cell, a High Temperature Innovative Dual mEmbrAne Fuel-Cell [PDF]

, 2009
IDEAL-Cell is a new concept of a high temperature fuel cell operating in the range 600-700°C. It is based on the junction between the anode part of a PCFC and the cathode part of a SOFC through a mixed H+ and O2- conducting porous ceramic membrane.
Stoynov, Z., A. Chesnaud, A. S. Thorel, D. Vladikova, Vladikova, D., BARBUCCI, ANTONIO, Presto, S., M. Viviani, Viviani, M., Chesnaud, A., Z. Stoynov, PICCARDO, PAOLO, S. Presto, Thorel, A.S, Ilhan, Zeynep, Piccardo, P, Z. Ilhan, Barbucci, A.   +17 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Effect of ε-Poly-L-lysine on Postharvest Diseases and Disease-Resistant Substance Metabolism in Passion Fruits [PDF]

Shipin Kexue
In order to investigate the inhibitory effect of ε-poly-L-lysine (ε-PL) on the occurrence of Lasiodiplodia theobromae-induced diseases and its correlation with disease resistance in postharvest passion fruits, harvested golden passion fruits (cv.
LIN Yuzhao, CHEN Leiyi, CHEN Jiayi, JIANG Xuanjing, ZHENG Jinshui, CHEN Hongbin
doaj   +1 more source

Determination of cell membrane permeability in concentrated cell ensembles

Biophysical Journal, 1987
The method of volume averaging is used to analyze the process of diffusion in concentrated cell ensembles in which significant resistance to mass transfer is caused by the cellular membrane. A general closure scheme is given that allows for direct theoretical prediction of effective diffusivities for any cellular geometry.
Ochoa, J.A., Whitaker, S., Stroeve, P.
openaire   +2 more sources

Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin [PDF]

, 2003
Gil-Parrado S, Assfalg-Machleidt I, Fiorino F, et al. Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. BIOLOGICAL CHEMISTRY.
Dominga Deluca, Schaschke, N., Gil-Parrado, S, Werner M.a.c.h.l.e.i.d.t., Luis Moroder, Dietmar Pfeiler, Irmgard Assfalg Machleidt, Machleidt, Werner, Fiorino, F, Pfeiler, D., Pfeiler, D, Machleidt, W, Schaschke, Norbert, Assfalg-Machleidt, Irmgard, Moroder, L, Deluca, D, Gil-Parrado, S., Moroder, L., Machleidt, W., Fiorino, F., Assfalg-Machleidt, I, Norbert Schaschke, Deluca, D., Assfalg-Machleidt, I., FIORINO, FERDINANDO, Shirley Gil Parrado   +25 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source