Results 41 to 50 of about 377,298 (310)
Cellular Physiology and Biochemistry, 2013 Background/Aims: Acetaminophen (APAP) effects on intestinal barrier properties are less investigated. APAP may lead to a changed bioavailability of a subsequently administered drug or diet in the body. We investigated the influence of APAP on enterocytic
Christine Schäfer +4 more
doaj +1 more source
Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]
, 2015 Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle +6 more
core +1 more source
Effect of proanthocyanidins on cell membrane properties of Saccharomyces cerevisiae [PDF]
Zhongguo niangzaoIn order to investigate the action mechanism of proanthocyanidins from the perspective of cell membrane, the effects of 0.5 g/L and 1.0 g/L proanthocyanidins on the characteristics of the cell membrane of Saccharomyces cerevisiae were studied.
DING Rui, ZHAO Hongwei, LI Jingyuan
doaj +1 more source
Continuous wave irradiation at 0.1 terahertz facilitates transmembrane transport of small molecules
iScience, 2022 Summary: The bioeffects of terahertz (THz) radiation received growing attention because of its influence on the interactions between biomolecules. Our work aimed to investigate the effects of THz irradiation on cell membrane, especially cell membrane ...
Erling Hu +4 more
doaj +1 more source
Sphingosine Increases the Permeability of Model and Cell Membranes [PDF]
Biophysical Journal, 2006 Sphingosine, at 5-15 mol % total lipids, remarkably increases the permeability to aqueous solutes of liposomal and erythrocyte ghost membranes. The increased permeability cannot be interpreted in terms of leakage occurring at the early stages of a putative membrane solubilization by sphingosine, nor is it due to a sphingosine-induced generation of ...
Contreras, F.-Xabier +3 more
openaire +3 more sources
Structure determination of membrane-located complexes: Aquaporin 8 and YscC secretin [PDF]
, 2011 A biological membrane is key to the life of a cell. In all living cells a biological membrane separates a inner life and an outer environment. Plasma membrane has many functions such as responding to external signals and transmitting them into the cell,
Kowal, Julia
core +1 more source
PLoS Pathogens, 2014 Non-enveloped viruses must deliver their viral genome across a cell membrane without the advantage of membrane fusion. The mechanisms used to achieve this remain poorly understood. Human rhinovirus, a frequent cause of the common cold, is a non-enveloped
Anusha Panjwani +9 more
doaj +1 more source
ANTAGONISTIC ACTION OF ELECTROLYTES AND PERMEABILITY OF THE CELL MEMBRANE [PDF]
Science, 1912 n ...
openaire +2 more sources
Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak
eLife, 2017 Cells deficient in the pro-death Bcl-2 family members Bax and Bak are known to be resistant to apoptotic cell death, and previous we have shown that these two effectors are also needed for mitochondrial-dependent cellular necrosis (Karch et al., 2013 ...
Jason Karch +6 more
doaj +1 more source
Pharmaceuticals, 2023 Protein drugs have been emerging as a class of promising therapeutics. However, their topical application has been limited by their high molecular weight and poor permeability to the cell membrane. In this study, we aimed to enhance human growth hormone (
Tru Van Nguyen +6 more
doaj +1 more source