Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation [PDF]
, 2009 CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by ...
Crompton, M. +7 more
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Diffusion in the Presence of Cells with Semi-permeable Membranes [PDF]
Journal of Statistical Physics, 2020 We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of the domain than to enter the interior of its complement, with a small parameter controlling the trapping mechanism ...
Freidlin, M., Koralov, L.
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Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane
Molecules, 2020 Due to the increasing use of antibiotics, measures are being taken to improve their removal from the natural environment. The support of biodegradation with natural surfactants that increase the bioavailability of impurities for microorganisms that ...
Monika Rojewska +3 more
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ANTAGONISTIC ACTION OF ELECTROLYTES AND PERMEABILITY OF THE CELL MEMBRANE [PDF]
Science, 1912 n ...
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Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes [PDF]
, 1994 Büntemeyer H, Bohme C, Lehmann J. Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes. Cytotechnology. 1994;15(1-3):243-251.In this study two microporous hollow fibre membranes were evaluated for their use
Lehmann, Jürgen +2 more
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Cellular Physiology and Biochemistry, 2013 Background/Aims: Acetaminophen (APAP) effects on intestinal barrier properties are less investigated. APAP may lead to a changed bioavailability of a subsequently administered drug or diet in the body. We investigated the influence of APAP on enterocytic
Christine Schäfer +4 more
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Continuous wave irradiation at 0.1 terahertz facilitates transmembrane transport of small molecules
iScience, 2022 Summary: The bioeffects of terahertz (THz) radiation received growing attention because of its influence on the interactions between biomolecules. Our work aimed to investigate the effects of THz irradiation on cell membrane, especially cell membrane ...
Erling Hu +4 more
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Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. [PDF]
, 2015 Oral absorption depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal absorption ...
Newby, Danielle +6 more
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Effect of proanthocyanidins on cell membrane properties of Saccharomyces cerevisiae [PDF]
Zhongguo niangzaoIn order to investigate the action mechanism of proanthocyanidins from the perspective of cell membrane, the effects of 0.5 g/L and 1.0 g/L proanthocyanidins on the characteristics of the cell membrane of Saccharomyces cerevisiae were studied.
DING Rui, ZHAO Hongwei, LI Jingyuan
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Sphingosine Increases the Permeability of Model and Cell Membranes [PDF]
Biophysical Journal, 2006 Sphingosine, at 5-15 mol % total lipids, remarkably increases the permeability to aqueous solutes of liposomal and erythrocyte ghost membranes. The increased permeability cannot be interpreted in terms of leakage occurring at the early stages of a putative membrane solubilization by sphingosine, nor is it due to a sphingosine-induced generation of ...
Contreras, F.-Xabier +3 more
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