Results 31 to 40 of about 9,017,426 (338)

Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study

open access: yesMembranes, 2022
Development of drugs that are selectively toxic to cancer cells and safe to normal cells is crucial in cancer treatment. Evaluation of membrane permeability is a key metric for successful drug development.
Navaneethan Radhakrishnan   +3 more
doaj   +1 more source

Significance of two transmembrane ion gradients for human erythrocyte volume stabilization.

open access: yesPLoS ONE, 2022
Functional effectiveness of erythrocytes depends on their high deformability that allows them to pass through narrow tissue capillaries. The erythrocytes can deform easily due to discoid shape provided by the stabilization of an optimal cell volume at a ...
F I Ataullakhanov   +3 more
doaj   +1 more source

Evaluations of Skin Permeability of Cannabidiol and Its Topical Formulations by Skin Membrane-Based Parallel Artificial Membrane Permeability Assay and Franz Cell Diffusion Assay

open access: yesMedical Cannabis and Cannabinoids, 2022
Introduction: Cannabinoids including cannabidiol (CBD) have attracted enormous interest as bioactive ingredients for various dermatological and/or cosmeceutical uses.
Riley D. Kirk   +7 more
doaj   +1 more source

Systematic comparison of unilamellar vesicles reveals that archaeal core lipid membranes are more permeable than bacterial membranes.

open access: yesPLoS Biology, 2023
One of the deepest branches in the tree of life separates the Archaea from the Bacteria. These prokaryotic groups have distinct cellular systems including fundamentally different phospholipid membrane bilayers.
Urszula Łapińska   +9 more
doaj   +1 more source

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

open access: yes, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Philippar, Katrin   +2 more
core   +1 more source

Analysis of Antimicrobial-Triggered Membrane Depolarisation Using Voltage Sensitive Dyes

open access: yesFrontiers in Cell and Developmental Biology, 2016
The bacterial cytoplasmic membrane is a major inhibitory target for antimicrobial compounds. Commonly, although not exclusively, these compounds unfold their antimicrobial activity by disrupting the essential barrier function of the cell membrane.
J. Derk te Winkel   +4 more
doaj   +1 more source

Diffusion in the Presence of Cells with Semi-permeable Membranes [PDF]

open access: yesJournal of Statistical Physics, 2020
We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of the domain than to enter the interior of its complement, with a small parameter controlling the trapping mechanism ...
Freidlin, M., Koralov, L.
openaire   +2 more sources

Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation [PDF]

open access: yes, 2009
CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by ...
Crompton, M.   +7 more
core   +1 more source

Valorisation of Shrimp Waste into Chitosan/Montmorillonite-Sulfosuccinic Acid Composite Membrane for DMFC Application

open access: yesReaktor, 2022
Composite membranes have been synthesized from biopolymer chitosan (CS) and nanosized montmorillonite (MMT) filler crosslinked with sulfosuccinic acid (SSA) as an alternative membrane electrolyte for direct methanol fuel cell (DMFC) application.
Shalahudin Nur Ayyubi   +2 more
doaj   +1 more source

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